AI Article Synopsis
- In 2020, significant research was published on systemic lupus erythematosus (SLE), particularly regarding genetic factors that play a role in its development.
- The review highlights novel therapeutic targets like IL-23, IL-17, and JAKs, as well as important biomarkers for diagnosis and prognosis.
- It also discusses new treatment options, especially belimumab and anifrolumab, and addresses factors affecting patients' perception of their disease and overall quality of life.
Article Abstract
In 2020 many contributions have been produced on SLE. Our critical digest of the recent literature will be focused on genetic factors that contribute to the development of the disease, novel potential therapeutic targets (including IL-23, IL-17, interferons and JAKs), diagnostic and prognostic biomarkers, classification criteria, clinical manifestations and comorbidities. We will then present new treatment options (with a special focus on belimumab, anifrolumab, tacrolimus, voclosporin and EULAR/ERA-EDTA recommendations for the management of LN) and treat-to-target strategy. Lastly, we will concentrate on some of the aspects that influence patients' disease perception and quality of life.
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| http://dx.doi.org/10.55563/clinexprheumatol/7gzsxp | DOI Listing |
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