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Investigation of the Content Offered to the Public Regarding Noise Pollution in Online News.
Noise Health
January 2025
Department of Public Health, William Paterson University, Wayne, New Jersey, USA.
Background/objectives: Noise remains an under-discussed type of environmental pollutant, which exerts a wide range of adverse health effects, both auditory and non-auditory. Ensuring that the public has ready access to useful health information online about noise exposure is important. In this regard, evaluating the content of public news articles regarding noise pollution is vital.
View Article and Find Full Text PDFAssociations of late mid‐life lifestyle with brain and cognitive changes in individuals on the AD vs. non‐AD continuum.
Alzheimers Dement
December 2024
Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin‐Madison School of Medicine and Public Health, Madison, WI, USA
Background: To aid development of prevention strategies, we investigated whether a composite measure of late‐midlife lifestyle health was associated with (1) change in brain tau burden, vascular burden and neurodegeneration and (2) cognitive trajectories when accounting for these brain changes.
Method: We included 324 individuals from the Wisconsin Registry for Alzheimer’s Prevention. Late‐midlife lifestyle was assessed using the Lifestyle for Brain Health (LIBRA) score, encompassing 12 risk‐and protective factors for cognitive decline and dementia.
Background: Brain‐derived neurotrophic factor (BDNF)—a key neurotrophin involved in synaptic plasticity, neurogenesis, and neuroprotection—has been shown to mediate sex differences in verbal learning and memory (VLM) ability, but it remains unclear whether this relationship is conditionally dependent upon carriage of the Val66Met polymorphism in the BDNF gene. This study investigates how BDNF carriage influences the mediation of sex differences in VLM scores by plasma BDNF levels in a cohort enriched for AD risk.
Method: Cognitively unimpaired participants in the Wisconsin Registry for Alzheimer’s Prevention (WRAP; n=198, age 63.
Early cortical microstructural neurodegeneration in aging is linked to vulnerability to Alzheimer’s disease pathology.
Alzheimers Dement
December 2024
University of California, San Diego, La Jolla, CA, USA
Background: Early identification of Alzheimer’s disease (AD) risk prior to irreversible brain damage is critical for improving the success of interventions and treatment. Cortical thickness is a macrostructural measure typically used to assess AD neurodegeneration. However, cortical microstructural changes appear to precede macrostructural atrophy and may improve early identification of AD risk.
View Article and Find Full Text PDFHow well does the RAQ measure up? Assessing attitudes toward research in a diverse community sample.
Alzheimers Dement
December 2024
Division of Geriatrics, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Background: Individuals’ attitudes toward research predict recruitment, engagement, and retention. The Research Attitudes Questionnaire (RAQ), developed to predict individuals’ willingness to participate, is often used in AD research. It can be used to identify strategies to mitigate individuals’ reluctance to engage in research.
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