We validated a multiplex bead assay for diphtheria toxoid IgG antibodies against the Vero cell toxin neutralization test using 1300 specimens (correlation = 0.88). At the ≥0.01 IU/mL cutoff for minimal seroprotection, sensitivity was 95% and specificity was 83%. Agreement for three categories (<0.01, 0.01-<0.1, ≥0.1 IU/mL) was 81% (kappa = 0.71).
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370405 | PMC |
| http://dx.doi.org/10.1016/j.diagmicrobio.2021.115371 | DOI Listing |
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