Dietary fiber is a group of heterogeneous substances that are neither digested nor absorbed in the small intestine. Some fibers can be classified as prebiotics if they are metabolized by beneficial bacteria present in the hindgut microbiota. The aim of this review was to specify the prebiotic properties of different subgroups of dietary fibers (resistant oligosaccharides, non-starch polysaccharides, resistant starches, and associated substances) to classify them by prebiotic categories. Currently, only resistant oligosaccharides (fructans [fructooligosaccharides, oligofructose, and inulin] and galactans) are well documented as prebiotics in the literature. Other fibers are considered candidates to prebiotics or have prebiotic potential, and apparently some have no prebiotic effect on humans. This dietary fiber classification by the prebiotic categories contributes to a better understanding of these concepts in the literature, to the stimulation of the processing and consumption of foods rich in fiber and other products with prebiotic properties, and to the development of protocols and guidelines on food sources of prebiotics.
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http://dx.doi.org/10.1016/j.nut.2021.111217 | DOI Listing |
Biomolecules
December 2024
Laboratory of Molecular Plant Biology and KU Leuven Plant Institute, Kasteelpark Arenberg 31, 3001 Leuven, Belgium.
Distinguishing between endo- and exo-type enzymes within the glycoside hydrolase (GH) classification presents significant challenges. Traditional methods, often based on endpoint activity measurements, do not capture the full range of products generated, leading to inconsistencies in classification. Not all exo-acting fructanases and glucanases produce monosaccharides (like fructose or glucose), while endo-acting enzymes do not solely produce higher-degree polymerization oligosaccharides.
View Article and Find Full Text PDFBenef Microbes
January 2025
Beneficial MicrobesConsultancy, Johan Karschstraat 3, 6709 TN Wageningen, The Netherlands.
Prebiotics are becoming increasingly recognized by consumers, health care professionals and regulators as important contributors to health. Nonetheless, the development, progress, and adoption of prebiotics is hindered by loose terminology, various misconceptions about sources and types of compounds that may be classified as prebiotics, and the lack of consensus on a definition that satisfies regulators. Evolving knowledge of the microbiome and its effects on host health has generated opportunities for modulation of the microbiota that can support host health.
View Article and Find Full Text PDFFront Microbiol
December 2024
Department of Epidemiology, Los Angeles Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Background: Bacteria play a crucial role in maintaining the health of human skin. Research has demonstrated that probiotics present notable benefits for extraintestinal organs. Despite the extensive research on the impact of probiotics on skin health, there is a notable absence of regulatory frameworks governing their external application, with no approval from the FDA for any probiotic products for external use.
View Article and Find Full Text PDFObes Rev
December 2024
Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France.
Background: Dysfunctional eating behaviors, and their modulators, are an important component in the prevalence of malnutrition. The gut microbiome, acting through the microbiota-gut-brain axis, is implicated as a modifiable factor in eating behavior. ObjectivesThis systematic review investigated the influence of the gut microbiome on human eating behavior and their modulators (appetite, satiety, energy/food intake, weight loss/gain).
View Article and Find Full Text PDFClin Nutr
January 2025
Section of Nutrition, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, W12 0NN, UK. Electronic address:
Background & Aims: Cancer therapy is associated with a range of toxicities that severely impact patient well-being and a range of clinical outcomes. Dietary fibre/prebiotics characteristically improve the gastrointestinal microenvironment, which consequently elicits beneficial downstream effects that could be relevant to the prevention and management of treatment-related toxicities. Despite the compelling theoretical scientific rationale there has been limited effort to synthesise the available evidence to conclude such scientific underpinning to the clinical use of fibre/prebiotics in cancer patients.
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