A stimulus-response system and conscious response enable humans to respond effectively to environmental changes and external stimuli. This paper presents an artificial stimulus-response system that is inspired by human conscious response and is capable of emulating it. The system is composed of an artificial visual receptor, artificial synapse, artificial neuron circuits, and actuator. By incorporating these artificial nervous components, a series of conscious response processes that markedly reduces response time as a result of learning from repeated stimuli are demonstrated. The proposed artificial stimulus-response system offers the promise of a new research field that would aid the development of artificial intelligence-based organs for patients with neurological disorders.
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http://dx.doi.org/10.1126/sciadv.abe3996 | DOI Listing |
Research (Wash D C)
October 2024
Department of Hepatobiliary Surgery, Academician (Expert) Workstation, Sichuan Digestive System Disease Clinical Medical Research Center, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, P. R. China.
Given the high malignancy of liver cancer and the liver's unique role in immune and metabolic regulation, current treatments have limited efficacy, resulting in a poor prognosis. Hydrogels, soft 3-dimensional network materials comprising numerous hydrophilic monomers, have considerable potential as intelligent drug delivery systems for liver cancer treatment. The advantages of hydrogels include their versatile delivery modalities, precision targeting, intelligent stimulus response, controlled drug release, high drug loading capacity, excellent slow-release capabilities, and substantial potential as carriers of bioactive molecules.
View Article and Find Full Text PDFMorphogen gradients convey essential spatial information during tissue patterning. While both concentration and timing of morphogen exposure are crucial, how cells interpret these graded inputs remains challenging to address. We employed an optogenetic system to acutely and reversibly modulate the nuclear concentration of the morphogen Dorsal (DL), homologue of NF-κB, which orchestrates dorso-ventral patterning in the embryo.
View Article and Find Full Text PDFBMJ Lead
December 2024
Department of Primary Health Care and General Practice, University of Otago, Wellington, New Zealand.
Objective: This scoping review seeks to understand how kindness, compassion and empathy are defined and conceptualised within existing healthcare services literature.
Introduction: Little consensus exists on how healthcare literature defines and conceptualises kindness. Kindness is often conflated with the terms compassion and empathy, which both have more prominence in the literature.
Mem Cognit
December 2024
Department of Psychology, University of Michigan at Ann Arbor, 530 Church Street, Ann Arbor, MI, 48109, USA.
Stroop-like interference effects are smaller in blocks of mostly incongruent (MI) trials than in blocks of mostly congruent (MC) trials. It is unclear, though, how control processes trigger this list-wide proportion congruency effect (LWPCE). The attentional shift account posits that a memory of experiencing conflict more frequently in MI blocks than in MC blocks leads control processes to shift attention toward the target in MI blocks.
View Article and Find Full Text PDFBMC Genomics
November 2024
Key Laboratory of Bio-Resources and Eco-Environment of Ministry of Education, College of Life Sciences, State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu, 610065, P. R. China.
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