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[Application of biomimetic restoration in oral-maxillofacial hard tissue repair]. | LitMetric

[Application of biomimetic restoration in oral-maxillofacial hard tissue repair].

Hua Xi Kou Qiang Yi Xue Za Zhi

State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shanxi Key Laboratory of Stomatology, School of Stomatology, Air Force Medical University, Xi,an 710032, China.

Published: April 2021

AI Article Synopsis

  • * The natural repair ability of this tissue is limited, necessitating the use of substitute materials, which often don't match the properties of human tissues, leading to ineffective repairs.
  • * Researchers are advancing biomimetic mineralization techniques to better mimic natural hard tissue properties, resulting in improved repair materials, with significant studies published in the last five years.

Article Abstract

Oral-maxillofacial hard tissue is the support of maxillofacial structure and appearance, and lays the foundation for functions of oral and maxillofacial system. Once the defect occurs, it will not only affect the physiological functions such as chewing and pronunciation, but also have a significant impact on the psychological and social life of patients. However, the self-repairing capability of the oral-maxillofacial hard tissue is pretty limited, in which case, substitute materials are required for tissue repair. A huge gap exists between the physical, chemical, structural characteristics of conventional substitute materials and those of human hard tissues, resulting in poor repair effect. Based on this, scholars simulated the process of biomineralization in the development of hard tissues, to improve the structure and function of materials through biomimetic mineralization technology and enhance the repair performance of materials. The current understanding of biomineralization theory and the construction of biomimetic repair technology is still in the stage of rapid development. In recent years, a mass of innovative studies are keeping emerging. In this review, the representative advances in the repair of oral-maxillofacial hard tissues of the past five years are reviewed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055765PMC
http://dx.doi.org/10.7518/hxkq.2021.02.002DOI Listing

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