Photodynamic therapy for radiation maculopathy: A case report.

Rationale: The best treatment protocol for radiation maculopathy in children has not been determined. The purpose of this study was to determine the effect of photodynamic therapy (PDT) on radiation maculopathy.

Patient Concerns: An 11-year-old boy who was originally diagnosed with orbital rhabdomyosarcoma when he was 1 year old, in October 2008. The lesion improved after peripheral blood stem cell transplantation, chemotherapy and radiation therapy. A cataract was detected in his right eye in May 2011, and he underwent cataract surgery in July 2011. Continuous amblyopia training maintained his visual acuity in his right eye. In January 2017, his visual acuity was reduced and macular edema was detected with optical coherence tomography.

Diagnoses: We diagnosed radiation maculopathy, from the history of radiation therapy, macular edema by optical coherence tomography, and hyperfluorescent site by fluorescein angiography.

Interventions: We performed PDT in June 2017.

Outcomes: Treatment with PDT improved macular edema and his visual acuity.

Lessons: Radiation retinopathy is progressive disorder with poor prognosis. PDT could be considered to treat radiation maculopathy.