Background: Dry needling (DN) has been consistently shown to decrease pain sensitivity and increase flexibility local to the site of treatment, however it is unclear whether these effects are limited to the region of treatment or can be observed remote to the area of treatment.
Objective: To determine the immediate, short-term effects of DN to the thoracolumbar junction on regional and remote flexibility, and to observe if changes in pain sensitivity can occur remote to site of treatment.
Design: Double-blind randomized clinical trial.
Methods: Fifty-four subjects with low back pain and decreased length in at least one hamstring were randomized to receive either DN or sham DN to the T12 and L1 multifidi. Participants underwent regional (fingertip-to-floor) and remote flexibility (passive knee extension, passive straight leg raise) and pressure pain threshold (PPT) testing of the upper and lower extremity before, immediately after and 1 day after treatment. ANCOVAs were used to analyze flexibility data, with the covariate of pre-treatment values. Paired t-tests were used for difference in remote pain sensitivity.
Results: Statistically larger improvements in regional flexibility, but not remote flexibility, were observed immediately post-treatment in those who received DN than in those receiving sham DN (p = .0495; adjusted difference 1.2, 95% CI 0.002-2.3). Differences between upper and lower extremity PPT were not significant.
Conclusion: DN can potentially have immediate changes in regional flexibility, but effects are not sustained at 24-h follow-up. DN may not affect remote flexibility or segmental pain sensitivity.
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http://dx.doi.org/10.1016/j.msksp.2021.102366 | DOI Listing |
Alzheimers Dement
December 2024
University of Florida, Gainesville, FL, USA.
Background: Remote administration of well-established neuropsychological instruments (TeleNeuropsychological or TeleNP) can reduce assessment wait times and expand access to cognitive assessments for medically compromised and socially disadvantaged patients. A major limitation in the widespread uptake of TeleNP relates to the need for more normative data compared to in-person assessments. This presentation describes a novel ascertainment strategy used in Florida's Older Adults TeleNeuropsychology (FLOAT) project to identify and recruit "cognitively healthy" older adults to norm well-established neuropsychological instruments administered remotely.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Background: Frontotemporal dementia (FTD) is a diverse spectrum of neurodegenerative disorders impacting the frontal and temporal lobes, primarily manifesting as behavioral and/or language issues. Accurate diagnosis is crucial for effective management, potential treatment, and care planning. While speech analysis has shown promise in detecting cognitive markers of Alzheimer's disease (AD), its exploration in FTD is limited.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Institute for Frontier Materials, Deakin University, Waurn Ponds, Victoria 3216, Australia.
Materials and devices that harvest acoustic energy can enable autonomous powering of microdevices and wireless sensors. However, traditional acoustic energy harvesters rely on brittle piezoceramics, which have restricted their use in wearable electronic devices. To address these limitations, this study involves the fabrication of acoustic harvesters using electrospinning of the piezoelectric polymer PVDF-TrFE onto fabric-based electrodes.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA.
Over 80% of biologic drugs, and 90% of vaccines, require temperature-controlled conditions throughout the supply chain to minimize thermal inactivation and contamination. This cold chain is costly, requires stringent oversight, and is impractical in remote environments. Here, we report chemical dispersants that non-covalently solvate proteins within fluorous liquids to alter their thermodynamic equilibrium and reduce conformational flexibility.
View Article and Find Full Text PDFCureus
November 2024
Department of Emergency Medicine, Ibn Sina Hospital, Makkah, SAU.
Emergency departments (EDs) encounter substantial challenges during peak vacation periods, including increased patient volumes, limited access to medical histories, language and cultural barriers, insurance complexities, and disruptions in continuity of care. These factors strain emergency department operations, resulting in prolonged wait times, diagnostic errors, and compromised care quality. This study reviews the literature to identify patient satisfaction indicators and common challenges and evaluate strategies to improve patient outcomes during vacation-related emergency department visits.
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