AI Article Synopsis
- Adoptees often lack access to information about hereditary diseases due to the absence of family medical history, affecting their health and access to screening programs.
- Genetic screening for asymptomatic adoptees may help identify potential health risks, but classifying genetic variants can be challenging, especially for certain ethnic groups and without family history.
- More research is needed to determine the effectiveness and usefulness of genetic screening in asymptomatic adoptees.
Article Abstract
Information regarding hereditary disease predisposition is generally inaccessible for adoptees. The lack of family history restricts access to various surveillance programmes and the overall health of the adoptee. Genetic screening of asymptomatic adoptees could be a compensational tool. However, variant classification is difficult, even more so in certain ethnic groups and in cases where there is no knowledge of family history, as summarised in this review. The usefulness of genetic screening of asymptomatic adoptees is still unknown and requires further research for clarification.
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