The last decade has seen a sharp increase in nematicide research in the agricultural industry. As a result, several new synthetic nematicides have become available to growers, and several more are expected in the near future. This new interest in nematicides is directly related to the growing demand for safer and more selective products, and the increasing regulatory pressure on many of the traditional nematicides. This has led to a ban of several widely used fumigant (e.g. methyl bromide) and non-fumigant (e.g. aldicarb) nematicides. The loss of traditional nematicides, combined with a lack of replacement products and awareness of the damage that nematodes can cause, has not only raised concern among growers, but has also created new opportunities for the crop protection industry. Nematicides have become a priority, and many companies are now allocating significant research dollars to discover new nematicides. The new nematicides are very different from previous products: (i) they are more selective, often only targeting nematodes, and (ii) they are less toxic, and safer to use. This review article describes these new developments by discussing the challenges that are associated with finding new nematicides, reviewing the nature, characteristics, and efficacy of new nematicides, and discussing the impact they could have on future nematode management.
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http://dx.doi.org/10.21307/jofnem-2020-091 | DOI Listing |
J Infect Dev Ctries
December 2024
Students' Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Introduction: Inflammation plays a role in coronavirus disease 2019 (COVID-19) pathophysiology and anti-inflammatory drugs may help reduce the disease severity. Levamisole is an anthelmintic drug with immunomodulatory and possible antiviral effects. This study aimed to evaluate the role of levamisole in the treatment of patients with COVID-19.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Laboratory of Agricultural Zoology and Entomology, Department of Science of Crop Production, Agricultural University of Athens, 11855 Athens, Greece.
The most common and damaging plant parasitic nematodes are root-knot nematodes (RNK). Although hemp has been clearly infected by RNK, little information is available regarding the extent of the damage and losses caused. In addition, no information is available concerning hemp seed extracts' activity against RNK.
View Article and Find Full Text PDFBiology (Basel)
January 2025
Plant Protection Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.
This study investigates the nematicidal efficacy of strain (AUMC 10620) combined with avermectin (B1a and B1b) against the citrus nematode , both in vitro and in vivo. Laboratory experiments tested four concentrations of (2.5, 5, 10, and 15 × 10 spores/mL) mixed with 250 ppm avermectin, assessing their effects on nematode juveniles (J2) and eggs.
View Article and Find Full Text PDFVet Parasitol Reg Stud Reports
January 2025
Tāwharau Ora - School of Veterinary Science, Massey University, Private Bag 11222, Palmerston North 4410, New Zealand.
Shortened egg reappearance periods (ERP) have been seen as an early warning of anthelmintic resistance development in cyathostomins in horses. The hypothesis has been that in these instances, efficacy against egg laying adult cyathostomins remains high, but a decline in activity against later larval stages leads to the earlier resumption of egg shedding after treatment. In this study using a single herd of horses we investigated the ERP of a number of commonly used equine anthelmintics and examined whether ERP might show seasonal variation between winter and summer.
View Article and Find Full Text PDFVet Parasitol Reg Stud Reports
January 2025
Department of Basic Medical Veterinary Sciences, Jordan University of Science & Technology, Irbid, Jordan.
This study aimed to identify the presence of gastrointestinal nematode populations resistant to albendazole, levamisole, and ivermectin in six farms located in three regions of Jordan (Irbid, Mafraq, and Ma'an). Infected sheep (40 per farm) with at least 100 eggs per gram were randomly divided into four groups (10 animals per group). Three groups were treated with ivermectin, albendazole, or levamisole while the fourth group was used as a negative control group.
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