AI Article Synopsis
- A case study highlights a rare type of adult cystic granulosa cell tumor (AGCT) in a 35-year-old woman who experienced infertility and hormonal imbalances.
- The diagnosis was confirmed through histopathology and genetic testing after a surgical procedure, leading to fertility preservation techniques before further surgery.
- This case suggests that AGCT should be considered in similar patients, and those seeking to maintain fertility should explore reproductive options before treatment.
Article Abstract
We report a rare subtype of adult cystic granulosa cell tumor (AGCT) characterized by elevated anti-Mullerian hormone and hyperandrogenism. A 35-year-old woman with primary infertility, hyperandrogenism, and irregular menses who was previously diagnosed with polycystic ovarian syndrome was diagnosed with AGCT based on histopathological examination and FOXL2 genetic test after laparoscopy. Due to fertility aspirations, she underwent controlled ovarian stimulation followed by embryo cryopreservation before salpingo-oophorectomy, and two embryos were frozen-thawed and transferred after surgery. A healthy female infant was delivered at 40 weeks' gestation. Cystic granulosa cell tumors should be considered a differential diagnosis in patients with persistent ovarian cysts and hyperandrogenism. Younger patients with AGCT with fertility goals should consider active assisted reproduction measures to preserve fertility before treatment for AGCT.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019939 | PMC |
| http://dx.doi.org/10.3389/fonc.2021.641166 | DOI Listing |
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