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| http://dx.doi.org/10.1136/bmjgh-2021-005261 | DOI Listing |
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Molecular epidemiology, evolution, and transmission dynamics of raccoon rabies virus in Connecticut.
Virus Evol
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Institute of Bioinformatics, University of Georgia, 120 Green St., Athens, GA 30602, United States.
In North America, raccoon rabies virus (RRV) is a public health concern due to its potential for rapid spread, maintenance in wildlife, and impact on human and domesticated animal health. RRV is an endemic zoonotic pathogen throughout the eastern USA. In 1991, an outbreak of RRV in Fairfield County, Connecticut, spread through the state and eventually throughout the Northeast and into Canada.
View Article and Find Full Text PDFPotential of Liposomal FTY720 for Bone Regeneration: Proliferative, Osteoinductive, Chemoattractive, and Angiogenic Properties Compared to Free Bioactive Lipid.
Int J Nanomedicine
January 2025
Pharmaceutical Technology Laboratory, Department of Pharmacy, University of Patras, Rion, 26504, Greece.
Introduction: FTY720 bioactive lipid has proliferative, osteoinductive, chemo attractive, and angiogenic properties, being thus a potential exogenous administered agent for promotion of bone regeneration. Herein we developed FTY720-loaded liposomes as a potential delivery system that could retain and prolong the bioactivity of the bioactive lipid and at the same time reduce its cytotoxicity (at high doses).
Methods: FTY720 liposomes were prepared by thin-lipid hydration and microfluidic flow focusing, and evaluated for their ability to induce proliferation, osteoinduction, and chemoattraction in three cell types: MC3T3-E1 pre-osteoblast cells, L929 fibroblast cells, and ATDC5 chondrogenic cells.
OGFr overexpression exerts anti-hepatocellular carcinoma effects by activating P16 and P21 to inhibit proliferation and migration of HepG2 cells.
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Department of Colorectal Surgery, Hangzhou Red Cross Hospital, Hangzhou, China.
Introduction: Hepatocellular carcinoma (HCC) is the sixth most common type of cancer and the second leading cause of cancer death worldwide [19]. Opioid growth factor (OGF) has been shown to exhibit antitumour potential, binding to OGF receptor (OGFr). Naltrexone (NTX), an OGFr antagonist, is considered as a potential anti-cancer agent.
View Article and Find Full Text PDFThe effect of degenerative scolioisis on segmental thoracolumbar sagittal alignment compared to age- and pelvic incidence-matched reference values.
Eur Spine J
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Service de Chirurgie du Rachis, Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, 1 Avenue Molière, Strasbourg, France.
Introduction: In asymptomatic subjects, variations of sagittal alignment parameters according to age and pelvic incidence (PI) has been reported. The aim of this observational study was to describe thoraco-lumbar sagittal alignment in patients with degenerative scoliosis and to compare them to asymptomatic individuals, seeking for the specific effect of deformity in similar age and PI groups.
Materials And Methods: Full spine radiographs of 235 asymptomatic subjects and 243 scoliosis patients were analyzed: cervico-thoracic inflexion point (CTIP), thoraco-lumbar inflexion point (TLIP), lumbar lordosis (LL) L1-S1, LL (TLIP-S1), LL superior arch (TLIP-lumbar apex), LL inferior arch (lumbar apex-S1), PI, thoracic kyphosis (TK) T5-T12, TK T1-T12, number of vertebrae CTIP-TLIPandTLIP-S1.
ZIF-67-derived NiCoO hollow nanocages coupled with g-CN nanosheets as Z-scheme photocatalysts for enhancing CO reduction.
J Colloid Interface Sci
January 2025
Key Laboratory of Beijing on Regional Air Pollution Control, Department of Environmental Science, College of Environmental Science & Engineering, Beijing University of Technology, Beijing 100124 China. Electronic address:
Photocatalytic CO reduction technology plays a significant role in the energy and environmental sectors, highlighting the necessity for developing high-efficiency and stable catalysts. In this study, a novel photocatalyst, xNiCoO/CN (x = 1, 3, and 5 wt%), was synthesized by depositing zeolitic imidazolate framework-67 (ZIF-67)-derived nickel cobaltate (NiCoO) hollow nanocages onto porous graphitic carbon nitride (g-CN, CN) nanosheets for photocatalytic CO reduction. Under visible light irradiation, the resulting 3NiCoO/CN photocatalyst demonstrated exceptional CO yields of up to 2879.
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