Background: Most comparisons of robot-assisted (RARC) versus open radical cystectomy (ORC) for urothelial carcinoma do not factor the inherent stage selection bias or surgical experience.
Methods: We compared the perioperative outcomes of 229 RARC and 335 ORC at a single tertiary referral centre with propensity score matching and multiple regression models, when controlling for tumour and patient characteristics, surgeon's experience and type of urinary diversion.
Results: RARC had less major complications (19.8% vs. 34.1%) and ICU admissions (6.6% vs. 19.8%), with lower blood loss (400 vs. 500 ml) and transfusion rates. The operating time was longer (336 vs. 286 min), but decreased with surgeon's experience. RARC had less positive surgical margins (3% vs. 8.4%) and a higher lymph node count (14 vs. 11).
Conclusions: In this large single centre series comparing RARC with ORC controlling for stage selection bias and surgical experience, RARC proved significantly better outcomes, especially with intracorporeal urinary diversion.
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http://dx.doi.org/10.1002/rcs.2258 | DOI Listing |
Br J Hosp Med (Lond)
January 2025
Department of Cardiology, The Second Affiliated Hospital of Chengdu Medical College, Nuclear Industry 416 Hospital, Chengdu, Sichuan, China.
Hypertension (HT) is a prevalent medical condition showing an increasing incidence rate in various populations over recent years. Long-term hypertension increases the risk of the occurrence of hypertensive nephropathy (HTN), which is also a health-threatening disorder. Given that very little is known about the pathogenesis of HTN, this study was designed to identify disease biomarkers, which enable early diagnosis of the disease, through the utilization of high-throughput untargeted metabolomics strategies.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Department of Oriental Medicine Resources, Sunchon National University, Suncheon 57922, Republic of Korea.
There is a growing need for sustainable, efficient methods to promote plant growth and protect crops, with plant extracts offering natural, multi-component solutions. Based on previous observations, , , and were selected from 17 water extracts to investigate how the application times of soil sprays affect the antioxidant enzymes and secondary metabolites in fruity and leafy vegetables at different growth stages. From 1 week after sowing (WAS) to 4 WAS, all applications increased the shoot fresh weight by 42-69% in cucumbers, 40-64% in tomatoes, 46-65% in kale and 42-63% in lettuce.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering and Technology Research Center of Coarse Cereal Industrialization, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Djulis ( Koidz.), a member of the family plant, is noted for its vibrant appearance and significant ornamental value. However, the mechanisms underlying color variation in its spikes remain unexplored.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Laboratory of Microbial Resource Biotechnology, Department of Agronomic and Veterinary Sciences, Sonora Institute of Technology, 5 de Febrero 818, Centro, Ciudad Obregón 85000, Sonora, Mexico.
The rapid growth of the human population has significantly increased the demand for food, leading to the intensification of agricultural practices that negatively impact the environment. Climate change poses a significant threat to global food production, as it can disrupt crop yields and modify the lifecycle stages of phytopathogens and pests. To address these challenges, the use of microbial inoculants, which are bioproducts containing beneficial microorganisms known as plant growth promotion microorganisms (PGPMs), has emerged as an innovative approach in sustainable agriculture.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Core Botanical Gardens/Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan 430074, China.
In constructed wetlands (CWs) with multiple plant communities, population structure may change over time and these variations may ultimately influence water quality. However, in CWs with multiple plant communities, it is still unclear how population structure may change over time and how these variations ultimately influence water quality. Here, we established a CW featuring multiple plant species within a polder to investigate the variation in plant population structure and wastewater treatment effect for drainage water over the course of one year.
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