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Fertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility.
Hum Reprod Update
January 2025
Amsterdam UMC, Location Vrije Universiteit Amsterdam, Centre of Expertise on Gender Dysphoria, Amsterdam, The Netherlands.
Background: Transgender and gender diverse (TGD) people seek gender-affirming care at any age to manage gender identities or expressions that differ from their birth gender. Gender-affirming hormone treatment (GAHT) and gender-affirming surgery may alter reproductive function and/or anatomy, limiting future reproductive options to varying degrees, if individuals desire to either give birth or become a biological parent.
Objective And Rationale: TGD people increasingly pursue help for their reproductive questions, including fertility, fertility preservation, active desire for children, and future options.
Twin testosterone transfer hypothesis and the second-to-fourth digit ratio in females of same-sex and opposite-sex twin pairs: An exploratory study.
Physiol Rep
January 2025
Department of Epidemiology, Biostatistics and Disease Control, University for Development Studies, Tamale, Ghana.
The twin testosterone transfer (TTT) hypothesis posits that females with male co-twins (opposite-sex, OS) might develop male-typical traits due to higher prenatal testosterone exposure. This study explored whether females of OS have lower 2D:4D digit ratios and higher testosterone levels compared to females of same-sex (SS) twin pairs. Conducted in Tamale from January to December 2022, the study included 40 participants aged 18-27 years: 10 males of OS, 10 females of OS, and 20 females of SS twin pairs.
View Article and Find Full Text PDFCorrigendum: Development and validation of dependence and craving measures specific to athletes who use anabolic-androgenic steroids.
Front Psychol
December 2024
School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
[This corrects the article DOI: 10.3389/fpsyg.2024.
View Article and Find Full Text PDFCorrection of meta-analysis after retraction of article on the effects of anti-androgens in polycystic ovary syndrome.
EClinicalMedicine
January 2025
Monash Centre for Health Research and Implementation (MCHRI), Monash University, Clayton, VIC, Australia.
[This corrects the article DOI: 10.1016/j.eclinm.
View Article and Find Full Text PDFSex Assignment in Cases of Ambiguous Genitalia.
Cureus
November 2024
Department of General Surgery, General Medicine Practice Program, Batterjee Medical College for Science and Technology, Jeddah, SAU.
Ambiguous genitalia is a rare disorder where it is unclear whether an infant's external genitals are male or female. This can be attributed to various internal and external etiologies, such as androgen receptor abnormalities, gonadal abnormalities (such as gonadal dysgenesis or Klinefelter syndrome where a male has an extra X chromosome), enzymatic defects, etc. Correction of such atypical genitalia requires a multidisciplinary approach, including but not limited to surgeons and therapists.
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