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| http://dx.doi.org/10.2147/AMEP.S311749 | DOI Listing |
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Beyond clinical observations: a scoping review of AI-detectable observable cues in borderline personality disorder.
Front Psychiatry
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Department of Psychology, Faculty of Arts, University of Maribor, Maribor, Slovenia.
Borderline Personality Disorder (BPD), impacting approximately 2% of adults worldwide, presents a formidable challenge in psychiatric diagnostics. Often underdiagnosed or misdiagnosed, BPD is associated with high morbidity and mortality. This scoping review embarks on a comprehensive exploration of observable cues in BPD, encompassing language patterns, speech nuances, facial expressions, nonverbal communication, and physiological measurements.
View Article and Find Full Text PDFAdvances in peptide/polymer antimicrobial assemblies.
J Mater Chem B
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State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun 130012, China.
Antimicrobial peptides (AMPs) have been extensively exploited as promising drugs to cope with antibiotic-resistant bacteria in clinical treatment. Peptide/polymer assembly provides a particularly important contribution to this topic and has emerged as a new paradigm for the development of nano-antimicrobial systems with previously unattainable outcomes. In this review article, we systematically summarize the recent advances in antimicrobial peptide/polymer assemblies.
View Article and Find Full Text PDFThe importance of microbiology reference laboratories and adequate funding for infectious disease surveillance.
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Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address:
Microbiology reference laboratories perform a crucial role within public health systems. This role was especially evident during the COVID-19 pandemic. In this Viewpoint, we emphasise the importance of microbiology reference laboratories and highlight the types of digital data and expertise they provide, which benefit national and international public health.
View Article and Find Full Text PDFFrom the 100 Day Mission to 100 lines of software development: how to improve early outbreak analytics.
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Infectious Disease Epidemiology and Dynamics, London School of Hygiene and Tropical Medicine, London, UK.
Since the COVID-19 pandemic, considerable advances have been made to improve epidemic preparedness by accelerating diagnostics, therapeutics, and vaccine development. However, we argue that it is crucial to make equivalent efforts in the field of outbreak analytics to help ensure reliable, evidence-based decision making. To explore the challenges and key priorities in the field of outbreak analytics, the Epiverse-TRACE initiative brought together a multidisciplinary group of experts, including field epidemiologists, data scientists, academics, and software engineers from public health institutions across multiple countries.
View Article and Find Full Text PDFZinc(II) organic framework based bifunctional biomarker sensor for efficient detection of urinary 5-Hydroxyindoleacetic acid and serum 3-Nitrotyrosine.
Spectrochim Acta A Mol Biomol Spectrosc
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School of Chemistry and Chemical Engineering, North University of China, Taiyuan 030051, PR China. Electronic address:
Monitoring biomarker levels in body fluids is of great importance in clinical diagnosis. Herein, a robust 3D ZnMOF, {[Zn(BTPB)(bib)(μ-OH)]·2HO}, was fabricated based on the ligands of 1,4-bis(2,4,6-tricarboxylpyrid-5-yl)benzene (HBTPB) and 1,4-bis(imidazol-1-yl)benzene (bib). On the basis of its stable architecture and intrinsic luminescence, ZnMOF demonstrated remarkable potential as a bifunctional luminescent sensor for selective and sensitive detecting the biomarkers of 3-nitrotyrosine (3-NT) and 5-hydroxyindoleacetic acid (5-HIAA) in water and body fluids by employing distinct "turn-off" and "turn-on" responses.
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