Concerns persist regarding possible false-negative results that may compromise COVID-19 containment. Although obtaining a true false-negative rate is infeasible, using real-life observations, the data suggest a possible false-negative rate of ˜2.3%. Use of a sensitive, amplified RNA platform should reassure healthcare systems.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111191 | PMC |
| http://dx.doi.org/10.1017/ice.2021.153 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
FilmArray® Effectively Detects All Clades of F41 but Encounters Challenges with Other Adenovirus Species.
J Infect Chemother
January 2025
Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan. Electronic address:
The BioFire FilmArray® Gastrointestinal (GI) Panel, a widely used diagnostic tool, is designed to detect the genetic material of 22 common pathogens responsible for gastroenteritis, including viruses, bacteria, and parasites. It can detect human adenovirus (HAdV) species F, particularly serotypes F40 and F41, which are the major causes of diarrhea and mortality in children. However, its potential shortcomings in detecting other HAdV species limit its effectiveness in broader HAdV detection in clinical settings and outbreak investigations.
View Article and Find Full Text PDFEstablishing quality assurance for COVID-19 antigen tests in the Indo Pacific Region: A multi-site implementation study.
Diagn Microbiol Infect Dis
December 2024
Department of Infectious Diseases, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, 3000, Australia; Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Victoria, 3000, Australia.
Background: Quality assurance programs (QAPs) are used to evaluate the analytical quality of a diagnostic test and provide feedback to improve quality processes in testing. Rapid diagnostic tests were used in both laboratory and non-laboratory settings to diagnose COVID-19, although varied in reported performance. We aimed to design and implement a QAP for antigen rapid diagnostic tests (Ag-RDTs) for COVID-19 in Cambodia, Lao PDR, and Papua New Guinea.
View Article and Find Full Text PDFClassification of Severity of Lung Parenchyma Using Saliency and Discrete Cosine Transform Energy in Computed Tomography of Patients With COVID-19.
Int J Telemed Appl
January 2025
Medical Familiar Unit, Instituto de Seguridad y Servicios Sociales de Los Trabajadores del Estado, Torreón, Coahuila, Mexico.
This study proposes an automated system for assessing lung damage severity in coronavirus disease 2019 (COVID-19) patients using computed tomography (CT) images. These preprocessed CT images identify the extent of pulmonary parenchyma (PP) and ground-glass opacity and pulmonary infiltrates (GGO-PIs). Two types of images-saliency () image and discrete cosine transform (DCT) energy image-were generated from these images.
View Article and Find Full Text PDFEconomic Evaluation of a Novel Lung Cancer Diagnostic in a Population of Patients with a Positive Low-Dose Computed Tomography Result.
J Health Econ Outcomes Res
September 2024
Avalon Health Economics, Coral Gables, Florida, USA.
Early detection of lung cancer is crucial for improving patient outcomes. Although advances in diagnostic technologies have significantly enhanced the ability to identify lung cancer in earlier stages, there are still limitations. The alarming rate of false positives has resulted in unnecessary utilization of medical resources and increased risk of adverse events from invasive procedures.
View Article and Find Full Text PDFOptimizing automated photo identification for population assessments.
Conserv Biol
January 2025
Marine Mammal Research Program, Hawai'i Institute of Marine Biology, University of Hawai'i at Mānoa, Kāne'ohe, Hawai'i, USA.
Several legal acts mandate that management agencies regularly assess biological populations. For species with distinct markings, these assessments can be conducted noninvasively via capture-recapture and photographic identification (photo-ID), which involves processing considerable quantities of photographic data. To ease this burden, agencies increasingly rely on automated identification (ID) algorithms.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!