Despite numerous research efforts, the precise mechanisms of concussion have yet to be fully uncovered. Clinical studies on high-risk populations, such as contact sports athletes, have become more common and give insight on the link between impact severity and brain injury risk through the use of wearable sensors and neurological testing. However, as the number of institutions operating these studies grows, there is a growing need for a platform to share these data to facilitate our understanding of concussion mechanisms and aid in the development of suitable diagnostic tools. To that end, this paper puts forth two contributions: (1) a centralized, open-access platform for storing and sharing head impact data, in collaboration with the Federal Interagency Traumatic Brain Injury Research informatics system (FITBIR), and (2) a deep learning impact detection algorithm (MiGNet) to differentiate between true head impacts and false positives for the previously biomechanically validated instrumented mouthguard sensor (MiG2.0), all of which easily interfaces with FITBIR. We report 96% accuracy using MiGNet, based on a neural network model, improving on previous work based on Support Vector Machines achieving 91% accuracy, on an out of sample dataset of high school and collegiate football head impacts. The integrated MiG2.0 and FITBIR system serve as a collaborative research tool to be disseminated across multiple institutions towards creating a standardized dataset for furthering the knowledge of concussion biomechanics.
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http://dx.doi.org/10.1038/s41598-021-87085-2 | DOI Listing |
Eur J Pharmacol
January 2025
Internal Medicine Office, Medical Education Centre, Western General Hospital, Edinburgh EH4 2XU, UK. Electronic address:
The IUPHAR Education Committee's Pharmacology Education Project (PEP; www.pharmacologyeducation.org) provides an open-access, peer-reviewed platform to support pharmacology education globally.
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January 2025
Learning and Capacity Development Unit, Health Emergencies Programme, World Health Organization, Geneva, Switzerland.
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Diabetes Care Unit, Caen University Hospital, Caen cedex 09, France.
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Department of Emergency Medicine, King Faisal Hospital, Makkah, SAU.
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Pathology, BLDE (Deemed to be University) Shri B.M. Patil Medical College, Hospital, and Research Centre, Vijayapura, IND.
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