AI Article Synopsis

  • The treatment approaches for retinoblastoma have changed significantly, with intraarterial chemotherapy being more effective and reducing the need for radiation, which can cause secondary cancers.
  • The standard treatment for pediatric nasopharyngeal carcinoma now includes induction chemotherapy followed by combined chemoradiation.
  • For adrenocortical carcinoma, surgery and chemotherapy are the primary treatments, while the use of radiation therapy is still being evaluated.

Article Abstract

The role of surgery, chemotherapy, and radiation therapy for retinoblastoma has evolved considerably over the years with the efficacy of intraarterial chemotherapy and the high incidence of secondary malignant neoplasms following radiation therapy. The use of spot scanning intensity-modulated proton therapy may reduce the risk of secondary malignancies. For pediatric nasopharyngeal carcinoma, the current standard of care is induction chemotherapy followed by chemoradiation therapy. For adrenocortical carcinoma, the mainstay of treatment is surgery and chemotherapy. The role of radiation therapy remains to be defined.

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Source
http://dx.doi.org/10.1002/pbc.28253DOI Listing

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