Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1001/jamainternmed.2021.0835 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bidirectional ventricular tachycardia due to digoxin-diuretic interaction in post-cardiac surgery patient: a case report.
Arch Peru Cardiol Cir Cardiovasc
June 2024
Hospital Regional Primero de Octubre ISSSTE, Mexico City, Mexico. Hospital Regional Primero de Octubre ISSSTE Mexico City Mexico.
Article Synopsis
- Bidirectional ventricular tachycardia (BVT) is a rare and serious heart rhythm issue marked by changes in the QRS axis with each heartbeat, often linked to digitalis toxicity.
- A 62-year-old woman who had heart surgery developed BVT after being treated with digoxin and diuretics, leading to concerns about the interaction between these medications.
- The case stresses the need for careful monitoring of digoxin levels in patients on diuretics and suggests supportive treatments if BVT occurs, like stopping digoxin and providing potassium and magnesium supplements.
Digoxin is rarely used in modern cardiovascular disease management. Therefore, digoxin toxicity has been infrequently encountered and it is paramount to diagnose in a timely fashion. Bidirectional ventricular tachycardia is an unusual arrhythmia wherein every other beat has a different QRS axis as it travels alternately down different conduction pathways.
View Article and Find Full Text PDFDigoxin-Induced Bidirectional Ventricular Tachycardia in a Patient With Hypokalemia.
JAMA Intern Med
June 2021
Preventive Cardiology and Vascular Medicine, Western Kentucky Heart and Lung, Bowling Green.
Rifampin and digoxin induction of MDR1 expression and function in human intestinal (T84) epithelial cells.
Br J Pharmacol
May 2008
Epithelial Research Group, Institute for Cell and Molecular Biosciences, University of Newcastle Upon Tyne, Medical School, Newcastle Upon Tyne, UK.
Background And Purpose: Oral drug bioavailability is limited by intestinal expression of P-glycoprotein (MDR1, Pgp, ABCB1) whose capacity is regulated via nuclear receptors e.g. the pregnane X receptor (PXR, SXR, NR1I2).
View Article and Find Full Text PDFImages in clinical medicine. Digoxin-induced bidirectional ventricular tachycardia.
N Engl J Med
February 1997
University of Colorado Health Sciences Center, Denver 80262, USA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!