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Synchronous clonally related anaplastic large cell lymphoma and malignant histiocytosis.
Diagn Pathol
January 2025
Laboratoire Hospitalier Universitaire de Bruxelles - Universitair Laboratorium Brussel, Université Libre de Bruxelles LHUB-ULB, Brussels, Belgium.
Background: Synchronous malignant histiocytoses are rare conditions that occur concurrently with another hematologic neoplasm. Most reported cases are associated with B-cell lymphoproliferative disorders, while associations with T-cell hemopathies are less common. These two diseases may share mutations and/or cytogenetic anomalies, which can lead to malignant proliferations.
View Article and Find Full Text PDFTeaching Pathological Physiology of Sepsis Using a High Fidelity Simulator.
Adv Physiol Educ
January 2025
Department of Pathological Physiology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Hnevotinska 3, Olomouc 775 15, Czech Republic.
A good knowledge of the theoretical foundations of medicine helps students and physicians to better recognize and treat patients with complex medical conditions, including sepsis and septic shock. The article describes the authors' experience in implementing the analysis of sepsis and septic shock using a high-fidelity simulated clinical scenario in the course of pathological physiology for preclinical medical students. The unique aspect of our approach is the integration of core physiology concepts, such as homeostasis, causality, structure-function relationships, and fundamental pathophysiology concepts (e.
View Article and Find Full Text PDFExtensive elastofibroma dorsi with scapulo-thoracic involvement in a male laborer: A case report.
Int J Surg Case Rep
January 2025
University of Tunis El Manar, Tunis Faculty of Medicine, 1007, Tunisia; Department of Orthopedic Surgery, Hospital Mongi Slim La Marsa, Tunisia.
Introduction And Importance: Elastofibroma dorsi is a rare benign soft tissue lesion primarily located in the subscapular region. This distinctive lesion, with its unique radiological and histological features, poses diagnostic challenges due to its subtle presentation and overlap with other conditions.
Case Presentation: A 48-year-old man, manual laborer with an unremarkable medical history presented with a progressively enlarging mass below the right scapula over two years.
Non-traumatic lumbar spondylolysis with contralateral pedicle and lamina fracture: a case report and review of the literature.
BMC Musculoskelet Disord
January 2025
Spine Center, Department of Orthopedics, Shanghai Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, No.415 Feng Yang Road, Shanghai, 200003, China.
Lumbar spondylolysis of a single lumbar vertebra with a fracture of the pedicle on the opposite side, as well as fractures of both pedicles and bilateral spondylolysis, have been extensively reported in the literature. These cases are commonly linked to factors such as trauma, sports activities, and spinal surgeries. We report a unique case of a unilateral lumbar spondylolysis with a fracture on the opposite side including the pedicle and lamina.
View Article and Find Full Text PDFEmbryonal tumor with multilayered rosettes, DICER1-mutated, showing histologically unique neuronal differentiation after chemoradiotherapy.
Neuropathology
January 2025
Department of Human Pathology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Embryonal tumors with multilayered rosettes (ETMRs) are rare and highly aggressive embryonal central nervous system tumors that predominantly affect infants younger than 3 years old. These tumors typically have a C19MC alteration (ETMR, C19MC-altered) or, more rarely, a DICER1 mutation (ETMR, DICER1-mutated). Post-chemotherapeutic or post-chemoradiotherapeutic histological changes of C19MC-altered ETMRs, such as maturation or loss of histological characteristics of ETMR have been described in several reports.
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