«OBESITY PARADOX» IN COMORBID STABLE ISCHEMIC HEART DISEASE AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS.

Objective: The aim: Was to find the possible relationship between spirometry tests, the BODE index (body mass index (BMI), airflow obstruction, dyspnea, and exercise tolerance) with bioimpedance parameters in overweight and class I obese patients.

Patients And Methods: Materials and methods: 47 patients with stable ischemic heart disease (IHD) (I-II functional class), chronic obstructive pulmonary disease (COPD) (GOLD II, III, IV; groups B, C, D) were divided into 3 groups: G1: 15 normal-weight patients, G2: 15 overweight subjects, and G3: 17 class I obese patients. Spirometry tests, bioimpedance parameters, 6MWT (6-minute walk test) were measured.

Results: Results: FEV1 was significantly higher in overweight (p = 0.033) and class I obese (p = 0.049) subjects, the BODE index was lower in overweight (p = 0.033) and class I obese (p = 0.037) patients, compared with normal-weight subjects. The statistically significant positive relationship was between BMI and FEV1 and the negative correlation was between BMI and the BODE index in all groups of patients (p < 0.05).

Conclusion: Conclusions: In our study, we found better FEV1, 6MWT, the BODE index, the statistically significant association between FEV1 and the BODE index with BMI in overweight and class I obese patients. That's why we can suppose the presence of the "obesity paradox" in comorbid overweight or class I obese stable IHD, COPD patients.