A composite material with temperature-humidity control functions was prepared by using sepiolite-zeolite powder as humidity control matrix and capric acid phase change microcapsules as temperature control material. The micromorphology, thermal conductivity, compressive strength, hygrothermal effect were studied by environmental scanning electron microscope (ESEM), thermal conductivity test, strength test and hygrothermal effect test, respectively. The results showed that the phase change temperature of capric acid phase change microcapsule is between 31 °C ~ 32 °C, the phase change enthalpy is 123.91 J/g, and it has good thermal stability. The humidity control performance is the best and the maximum humidity absorption rate is 6.28% when sepiolite-zeolite powder ratio is 9:1. The humidity control matrix@CAM (Capric acid microcapsules) can control the relative humidity of the environment at 51.74 ~ 58.54% and reduce the temperature fluctuation range by 2 °C ~ 3 °C. Capric acid phase change microcapsules are embedded in the interlaced sepiolite and zeolite powder to form a frame space body which produce capillary condensation adsorption and surface adsorption, absorb and desorb heat through phase changes, thus giving humidity control matrix@CAM a good temperature-humidity control performance.
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http://dx.doi.org/10.1016/j.jcis.2021.03.106 | DOI Listing |
Mol Pharm
March 2025
Merck & Co., Inc., Rahway, New Jersey 07065, United States.
This is the fourth paper in a series describing an inhalation biopharmaceutics classification system (iBCS), an initiative supported by the Product Quality Research Institute. The paper examines the application of the inhalation Biopharmaceutics Classification System (iBCS) through the drug discovery, development, and postapproval phases for orally inhaled drug products (OIDP) and for the development of generic OIDPs. We consider the implication of the iBCS class in terms of product performance and identify the practical gaps that must be filled to enable the classification system to be adopted into day-to-day practice.
View Article and Find Full Text PDFCancer Med
March 2025
Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA.
Introduction: Distress is common among cancer patients, especially those undergoing surgery. However, no study has systematically analyzed distress trends in this population. The purpose of this study was to systematically review perioperative rates of distress, as well as differences across cancer types, in cancer patients undergoing surgical intervention.
View Article and Find Full Text PDFSemin Ophthalmol
March 2025
Department of Ophthalmology, Peking University People's Hospital, Beijing, China.
Purpose: To evaluate and contrast the effectiveness and safety of two conbercept treatment protocols-a three-dose treat-and-extend (3+T&E) regimen and a three-dose pro re nata (3+PRN) regimen-in Chinese patients diagnosed with neovascular age-related macular degeneration (nAMD).
Methods: Eligible patients, who had not undergone anti-VEGF intraocular injections within 3 months prior to enrollment, were randomly assigned to either the 3+T&E or 3+PRN regimen. The 3+T&E group received at least three monthly injections, with subsequent visit intervals extended based on disease activity assessment.
Front Immunol
March 2025
Semmelweis University, Department of Physiology, Budapest, Hungary.
Objective: Contact hypersensitivity (CHS), or allergic contact dermatitis (ACD), is an inflammatory skin disorder characterized by an exaggerated allergic reaction to specific haptens. During this delayed-type allergic reaction, the first contact with the allergen initiates the sensitization phase, forming memory T cells. Upon repeated contact with the hapten, the elicitation phase develops, activating mostly macrophages, cytotoxic T cells, and neutrophilic granulocytes.
View Article and Find Full Text PDFR Soc Open Sci
March 2025
National University of Science and Technology, MISIS, Moscow, Russia.
Currently, replacing expensive and short-lived materials for supercapacitors based on RuO with more cost-effective and high-performance materials that remain operational after a large number of cycles is a challenge. Cerium-based materials are the most attractive alternative because of cerium's ability to quickly change oxidation state. This work proposes the synthesis of nanostructured graphene-ceria composite and studies its morphological features arising under the impact of oxygen-free graphene.
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