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Case report: a 3-year follow-up on nodal marginal zone lymphoma coexisting with disseminated Talaromyces marneffei infection in a non-endemic area.
Front Oncol
January 2025
Department of Pathology, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Zhejiang, Yiwu, China.
This case report presents the details of an elderly man in Zhejiang Province of China, who tested human immunodeficiency virus (HIV) negative and subsequently developed Nodal Marginal Zone Lymphoma (NMZL) along with disseminated infection. The study focuses on analyzing the distinct clinical symptoms and pathological manifestations in order to offer precise diagnosis and effective treatment for patients. A 76-year-old male patient was admitted to our hospital due to recurrent fever.
View Article and Find Full Text PDFDisseminated talaromycosis: Truly uncommon or uncommonly recognized?
Med J Armed Forces India
December 2024
Brig Med, HQ 2 Corps, C/o 56 APO, India.
34 years old male from north-east India, a known case of retroviral disease, presented with shortness of breath and significant weight loss and was found to have pancytopenia, skin lesions, organomegaly, generalized lymphadenopathy, cavitary lung disease with very low CD4 counts. He failed to improve on empirical antitubercular therapy and further evaluation revealed features of disseminated talaromycosis on bone marrow studies. We hereby present an interesting case of a systemic fungal disease in the setting of advanced HIV infection.
View Article and Find Full Text PDFTalaromyces marneffei central nervous system infection unveiled by the novel Mp1p antigen detection assay in AIDS patient.
BMC Infect Dis
December 2024
Central Laboratory, Chongqing Public Health Medical Centre, Chongqing, China.
Background: In acquired immunodeficiency syndrome patients, Talaromyces marneffei infections are mostly disseminated and may involve the skin, mucosa, respiratory system, digestive system, lymphatic system, and as some reports indicate, the nervous system. Mp1p, a cell wall-specific polysaccharide in Talaromyces marneffei, is used for laboratory diagnosis of Talaromyces marneffei in blood and urine samples. However, Cerebrospinal fluid Mp1p diagnosis of Talaromyces marneffei central nervous system infection has not been reported.
View Article and Find Full Text PDFDisseminated Combined and Bloodstream Infection Presenting as Gastrointestinal Perforation in a Patient with CARD9 Gene Mutation.
Infect Drug Resist
October 2024
Department of Laboratory Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, People's Republic of China.
This study presents a case of combined with bloodstream infection with gastrointestinal symptoms as the sole initial clinical manifestation.The patient is a resident of Shanghai and has no recent travel history to areas with a high risk of infection. He was admitted to the emergency room due to severe upper abdominal pain.
View Article and Find Full Text PDFCharacteristics of Endemic Mycoses Talaromyces marneffei Infection Associated with Inborn Errors of Immunity.
J Clin Immunol
September 2024
Department of Rheumatology & Immunology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Background: Talaromyces marneffei (T. marneffei) is an opportunistic pathogen that causes endemic mycoses, which could lead to multiple organ damage. Talaromycosis is frequently disregarded as an early cautionary sign of immune system disorders in non-HIV-infected children.
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