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| http://dx.doi.org/10.1016/j.tranon.2021.101040 | DOI Listing |
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Not just a garbage truck: No-go decay plays a role during embryo development in zebrafish.
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Department of Biology, Washington University in St. Louis, St. Louis, Missouri, United States of America.
In eukaryotes, defective mRNAs that impede the movement of the ribosome are subject to rapid decay via no-go decay (NGD). In this issue of PLOS Biology, Ishibashi and colleagues expand on the role of NGD and reveal new endogenous targets for the process in zebrafish.
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In this editorial we comment on the article by Safwan M . We especially focused on the cardiac function restoration by the use of mesenchymal stem cells (MSCs) therapy for heart failure (HF), which has emerged as a new treatment approach as "Living Biodrugs". HF remains a significant clinical challenge due to the heart's inability to pump blood effectively, despite advancements in medical and device-based therapies.
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