Evidence will be presented to show that the allyl group is suitable for the protection of a 3'-terminal phosphodiester function. The latter will be demonstrated by the synthesis, via a phosphotriester approach, of two cyclic tetraribonucleotides [r(AAAA) and r(UAMe2UAMe2)], two cyclic hexadeoxyribonucleotides [d(CGCGCG) and d(TAAAAA)] and a cyclic octadeoxyribonucleotide [d(CGTGCGTG)].
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC336652 | PMC |
| http://dx.doi.org/10.1093/nar/16.10.4607 | DOI Listing |
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