AI Article Synopsis
- The study focuses on creating and testing composite coatings made of polylactic acid (PLA) that include iron oxide nanoparticles modified with Eucalyptus essential oil.
- Various sophisticated techniques were used to analyze the composition and structure of these nanoparticles and the resulting thin films.
- The coatings showed biocompatibility with stem cells and were effective against bacterial biofilms, indicating potential for medical applications.
Article Abstract
The present study reports on the development and evaluation of nanostructured composite coatings of polylactic acid (PLA) embedded with iron oxide nanoparticles (FeO) modified with Eucalyptus () essential oil. The co-precipitation method was employed to synthesize the magnetite particles conjugated with Eucalyptus natural antibiotic (FeO@EG), while their composition and microstructure were investigated using grazing incidence X-ray diffraction (GIXRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), transmission electron microscopy (TEM) and dynamic light scattering (DLS). The matrix-assisted pulsed laser evaporation (MAPLE) technique was further employed to obtain PLA/FeO@EG thin films. Optimal experimental conditions for laser processing were established by complementary infrared microscopy (IRM) and scanning electron microscopy (SEM) investigations. The in vitro biocompatibility with eukaryote cells was proven using mesenchymal stem cells, while the anti-biofilm efficiency of composite PLA/FeO@EG coatings was assessed against Gram-negative and Gram-positive pathogens.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036921 | PMC |
| http://dx.doi.org/10.3390/ma14071612 | DOI Listing |
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