The cultivation of the cellulolytic bacterium, , can have cost-effective cellulosic biomass utilizations, such as consolidated bioprocessing, simultaneous biological enzyme production and saccharification. However, these processes require a longer cultivation term of approximately 1 week. We demonstrate that constituents of the membrane vesicle fraction significantly promoted the growth rate of . Similarly, cell-free broth was able to increase growth rate, while several single-gene deletion mutants, e.g., , , , , , decreased the growth stimulation ability. Metabolome analysis revealed signal compounds for cell-cell communication in the membrane vesicle fraction (ethyl 2-decenoate, ethyl 4-decenoate, and 2-dodecenoic acid) and broth (nicotinamide, indole-3-carboxaldehyde, urocanic acid, nopaline, and 6-paradol). These findings suggest that the constituents in membrane vesicles from and could promote growth, leading to improved efficiency of cellulosic biomass utilization.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002186 | PMC |
| http://dx.doi.org/10.3390/microorganisms9030593 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Inferring structure of cortical neuronal networks from activity data: A statistical physics approach.
PNAS Nexus
January 2025
Department of Mathematics, Aston University, Birmingham B4 7ET, United Kingdom.
Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve over time, spontaneously or under stimulation. It requires a method for inferring the structure and composition of a network from neuronal activities. Tracking the evolution of networks and their changing functionality will provide invaluable insight into the occurrence of plasticity and the underlying learning process.
View Article and Find Full Text PDFExploring caffeine as a disruptor of membrane integrity and genomic stability in Staphylococcus aureus: functional and in silico analysis.
Arch Microbiol
January 2025
School of Basic and Applied Sciences, Department of Biological Sciences, Dayananda Sagar University, Innovation Campus, Kudlu Gate, Hosur Rd, Bengaluru, 560 068, India.
To explore the mechanistic underpinnings of caffeine as a potent antibacterial against Staphylococcus aureus ATCC 25923 via in vitro functional assays, whole-genome sequencing, and in silico docking studies. In vitro studies established that caffeine's minimum inhibitory concentration (MIC) against S. aureus ATCC 25923 is 0.
View Article and Find Full Text PDFGalangin synergistically revives the antibacterial activity of vancomycin against vancomycin-resistant Enterococcus faecium.
J Appl Microbiol
January 2025
School of Preclinical Sciences, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Aims: Enterococcus faecium is one of the most important opportunistic pathogens threatening human health worldwide. Resistance to vancomycin (VAN) is increasing at an alarming rate. Resurrecting antibiotics using a combination approach is a promising alternative avenue.
View Article and Find Full Text PDFPlantaginis Herba attenuates adriamycin-induced nephropathy: Molecular mechanism insights by integrated transcriptomic and experimental validation.
J Ethnopharmacol
January 2025
Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, 156 Jinshui East Road, Zhengzhou 450046, China. Electronic address:
Ethnopharmacological Relevance: The Chinese herbal Plantaginis Herba (PL) is one of the most widely used plants for both medicinal and dietary purposes. Plantaginis Herba is the main medicine used in a traditional Chinese prescription called Cheqiancao decoction, and it is known for its liver and kidney protective properties.
Aim Of The Study: The aim of the present study was to explore the interventions and mechanisms of PL in ADR nephropathy by performing an integrated analysis of in vitro and in vivo experiments.
Colistin Resistance Mechanism and Management Strategies of Colistin-Resistant Infections.
Pathogens
November 2024
Smart Animal Bio Institute, Dankook University, Cheonan 31116, Republic of Korea.
The emergence of antibiotic-resistant () is a pressing threat in clinical settings. Colistin is currently a widely used treatment for multidrug-resistant , serving as the last line of defense. However, reports of colistin-resistant strains of have emerged, underscoring the urgent need to develop alternative medications to combat these serious pathogens.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!