AI Article Synopsis

  • Bacterial endophthalmitis is a serious eye infection that can lead to fast vision loss, with two types: exogenous (ExE) from outside the body and endogenous (EnE) from within.
  • A study of 314 Japanese patients found older individuals with more severe symptoms were more common in the ExE group, but visual recovery outcomes (BCVA) were similar for both types.
  • Risk factors for poor visual outcomes included eye pain, identifying the bacteria causing the infection, and having low BCVA at the start of treatment.

Article Abstract

Bacterial endophthalmitis is an intraocular infection that causes rapid vison loss. Pathogens can infect the intraocular space directly (exogenous endophthalmitis (ExE)) or indirectly (endogenous endophthalmitis (EnE)). To identify predictive factors for the visual prognosis of Japanese patients with bacterial endophthalmitis, we retrospectively examined the bacterial endophthalmitis characteristics of 314 Japanese patients and performed statistics using these clinical data. Older patients, with significantly more severe clinical symptoms, were prevalent in the ExE group compared with the EnE group. However, the final best-corrected visual acuity (BCVA) was not significantly different between the ExE and EnE groups. Bacteria isolated from patients were not associated with age, sex, or presence of eye symptoms. , and were more prevalent in ExE patients than EnE patients and contributed to poor final BCVA. The presence of eye pain, bacterial identification, and poor BCVA at baseline were risk factors for final visual impairment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063932PMC
http://dx.doi.org/10.3390/pathogens10040390DOI Listing

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