Oxidative Stress and Endoplasmic Reticulum Stress in Rare Respiratory Diseases.

J Clin Med

Research Group on Rare Respiratory Diseases (ERR), Department of Physiology, School of Medicine, University of Valencia, Avda. Blasco Ibáñez, 15, 46010 Valencia, Spain.

Published: March 2021

Several studies have shown that some rare respiratory diseases, such as alpha-1 antitrypsin deficiency (AATD), idiopathic pulmonary fibrosis (IPF), cystic fibrosis (CF), and primary ciliary dyskinesia (PCD) present oxidative stress (OS) and endoplasmic reticulum (ER) stress. Their involvement in these pathologies and the use of antioxidants as therapeutic agents to minimize the effects of OS are discussed in this review.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003245PMC
http://dx.doi.org/10.3390/jcm10061268DOI Listing

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