AI Article Synopsis
- Gotland sheep, native to Gotland, Sweden, split from the Gute sheep breed about 100 years ago and has gained popularity for its high-quality pelts.
- A study analyzed 600 K SNP genotype data to estimate shared ancestors and identify genetic selection signatures, finding the Gotland breed is distinct yet shares ancestry with several other breeds.
- Significant SNPs linked to candidate genes impacting wool quality, fertility, and growth traits were identified, offering insights into the genetics underlying important economic traits in sheep.
Article Abstract
Gotland sheep, a breed native to Gotland, Sweden (an island in the Baltic Sea), split from the Gute sheep breed approximately 100 years ago, and since, has probably been crossed with other breeds. This breed has recently gained popularity, due to its pelt quality. This study estimates the shared ancestors and identifies recent selection signatures in Gotland sheep using 600 K single nucleotide polymorphism (SNP) genotype data. Admixture analysis shows that the Gotland sheep is a distinct breed, but also has shared ancestral genomic components with Gute (~50%), Karakul (~30%), Romanov (~20%), and Fjällnäs (~10%) sheep breeds. Two complementary methods were applied to detect selection signatures: A Bayesian population differentiation F and an integrated haplotype homozygosity score (iHS). Our results find that seven significant SNPs (-value < 0.05) using the F analysis and 55 significant SNPs (-value < 0.0001) using the iHS analysis. Of the candidate genes that contain significant markers, or are in proximity to them, we identify several belongings to the keratin genes, , , , , , , , , , and . These genes are involved in wool quality, polled and horned phenotypes, fertility, twining rate, meat quality, and growth traits. In summary, our results provide shared founders of Gotland sheep and insight into genomic regions maintained under selection after the breed was formed. These results contribute to the detection of candidate genes and QTLs underlying economic traits in sheep.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002741 | PMC |
| http://dx.doi.org/10.3390/genes12030433 | DOI Listing |
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Article Synopsis
- Gotland sheep, native to Gotland, Sweden, split from the Gute sheep breed about 100 years ago and has gained popularity for its high-quality pelts.
- A study analyzed 600 K SNP genotype data to estimate shared ancestors and identify genetic selection signatures, finding the Gotland breed is distinct yet shares ancestry with several other breeds.
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