A new approach of Fiber Enhanced Raman Spectroscopy (FERS) is described within this article based on the use of Hydrogel-Core microstructured Polymer Optical Fibers (HyC-mPOF). The incorporation of the hydrogel only on the core of the Hollow-Core microstructured Polymer Optical Fiber (HC-mPOF) enables to perform FERS measurements in a functionalized matrix, enabling high selectivity Raman measurements. The hydrogel formation was continuously monitored and quantified using a Principal Component Analysis verifying the coherence between the components and the Raman spectrum of the hydrogel. The performed measurements with high and low affinity target molecules prove the feasibility of the presented HyC-mPOF platform.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961415 | PMC |
| http://dx.doi.org/10.3390/s21051845 | DOI Listing |
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