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| http://dx.doi.org/10.1093/asjof/ojab006 | DOI Listing |
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Pharmacogenomic curriculum in Australian medical schools: a content analysis study.
Pharmacogenomics
January 2025
School of Pharmacy, Faculty of Health and Behavioural Sciences, University of Queensland, Woolloongabba, Australia.
Aims: To ascertain and describe pharmacogenomic concepts included in the intended curriculum of accredited Australian medical schools.
Methods: Content analysis of curriculum learning objectives of Australian medical schools was conducted, focusing on keywords and phrases pertaining to pharmacogenomic education. Learning objectives related to pharmacogenomics were categorized using (1) undergraduate medical genomic competencies per the Association of Professors in Human and Medical Genetics (2) Bloom's Taxonomy for cognitive and knowledge dimensions and (3) knowledge translation (enabling science, translation science and clinical implementation).
Timing of pre-retrieval warnings matters in reducing memory errors in a repeated testing misinformation study.
Sci Rep
January 2025
Department of Psychology, Tufts University, Medford, MA, USA.
Individuals are often exposed to information regarding previously witnessed events. The misinformation effect occurs when inaccurate post-event information impairs accuracy on a subsequent test of memory for the original event. The misinformation effect is increased when a test is given prior to exposure to post-event information, a phenomenon termed Retrieval Enhanced Suggestibility (RES).
View Article and Find Full Text PDFChronic kidney disease-associated pruritus: a comparison of instruments and associations with patient-reported outcomes using an electronic patient-reported outcome survey in Europe.
Clin Kidney J
October 2024
Arbor Research Collaborative for Health, Ann Arbor, USA.
Background: The associations between self-reported chronic kidney disease-associated pruritus (CKD-aP) and patient-reported outcomes (PROs) have been reported using various instruments to assess itch. Data collection via multiple CKD-aP instruments allows the evaluation of different domains and measurements of CKD-aP burden and may help tailor data capture for future research or clinical care.
Methods: An electronic PRO (ePRO) survey was distributed to European hemodialysis (HD) patients enrolled in the Dialysis Outcomes and Practice Patterns Study (DOPPS) in 2021-23.
Multi-regional control of amygdalar dynamics reliably reflects fear memory age.
Nat Commun
December 2024
Laboratory for Circuit and Behavioral Physiology, RIKEN Center for Brain Science, Wako-shi, Saitama, Japan.
The basolateral amygdala (BLA) is crucial for the encoding and expression of fear memory, yet it remains unexplored how neural activity in this region is dynamically influenced by distributed circuits across the brain to facilitate expression of fear memory of different ages. Using longitudinal multisite electrophysiological recordings in male mice, we find that the recall of older contextual fear memory is accompanied by weaker, yet more rhythmic, BLA gamma activity which is distally entrained by theta oscillations in both the hippocampal CA1 and the anterior cingulate cortex. Computational modeling with Light Gradient Boosting Machine using extracted oscillatory features from these three regions, as well as with Transformer using raw local field potentials, accurately classified remote from recent memory recall primarily based on BLA gamma and CA1 theta.
View Article and Find Full Text PDFMemory modulation: Dominance of negative visual context over neutral verbal memory.
PLoS One
October 2024
School of Psychological Sciences, Tel Aviv University, Tel Aviv, Israel.
Article Synopsis
- Neutral memories can be influenced through techniques like directed forgetting, but negative visual contexts can undermine this process.
- In an experiment, participants struggled to remember neutral verbal information when it was presented alongside negative images, showing that negative visuals strongly impact memory retention.
- The negative visual memories not only persisted over time but were also resistant to methods that previously worked for modulating other types of memories, indicating a significant challenge for those dealing with negative memories in mental health contexts.
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