Objective: To analyze the relevance of clinical indicators and the clarity and precision of conceptual and operational definitions of the diagnosis Impaired gas exchange.
Methods: Content analysis, by 39 nurse judges, divided into the phases of conceptual definition of the phenomenon of interest, construction of the structure of the phenomenon of interest and analysis of the judges on the built structure.
Results: From the 22 indicators, 21 were considered relevant Impaired gas exchange. The indicators that obtained absolute relevance were Cyanosis, Hypercapnia, Hypoxemia and Tachycardia. The indicator Headache upon waking did not show any statistically significant relevance for the diagnosis. All conceptual and operational definitions were clear and precise.
Conclusion: The indicators listed for Impaired gas exchange were relevant to the phenomenon, except Headache upon waking because it does not correspond to a safe manifestation to identify the diagnosis, according to the analysis of the judges. Each conceptual and operational definition was adequate for its indicator.
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http://dx.doi.org/10.1590/1983-1447.2021.20200099 | DOI Listing |
Int Dent J
December 2024
Department of Restorative Dentistry, Hamdan Bin Mohammed College of Dental Medicine (HBMCDM), Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai Health, Dubai, United Arab Emirates; Department of Restorative Dentistry, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. Electronic address:
Background And Aim: Recent studies have shown that electronic cigarettes (ECs) use disrupts the oral microbiome composition and diversity, impairing the metabolic pathways of the mucosal cells. However, to date, no reports have evaluated the role of EC exposure in the context of oral metabolome. Hence, the aim of this study was to investigate the role of EC aerosol exposure in the dysregulation of the oral microbiome and metabolome profile using in vitro 3D organotypic models of human oral mucosa.
View Article and Find Full Text PDFTissue Cell
December 2024
Department of Neurosurgery, Huabei Petroleum Administration Bureau General Hospital, Renqiu, Hebei Province 062550, China. Electronic address:
Introduction: Acute lung injury (ALI) is the critical respiratory condition. Syringin with anti-inflammatory and anti-oxidant properties can exhibit the lung protective effects. SIRT1 and STAT6 can exert protective roles against lung injury by inhibiting ferroptosis.
View Article and Find Full Text PDFJ Environ Manage
December 2024
School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, 11794, USA.
Climate change has significantly altered fish population dynamics and marine ecosystems worldwide, resulting in multiple ecological, economic and social risks for sustainable fisheries. As a hotspot of global warming, China is anticipated to face with extensive climate-driven changes in marine fisheries and ecosystems, but a clear and adaptative management strategy has not been established. In this study, we assessed the climate adaptiveness of current fisheries management and alternative strategies with diverse management priorities.
View Article and Find Full Text PDFEnviron Int
December 2024
Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA; Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, CA, USA.
Background: Air pollution may impair child growth and cognitive development, with potential markers including birth length and head circumference.
Methods: The Household Air Pollution Intervention Network (HAPIN) trial was an open label multi-country-randomized controlled trial, with 3200 pregnant women aged 18-34 years (9-19 weeks of gestation) randomly assigned in a 1:1 ratio to receive liquefied petroleum gas (LPG) stove intervention compared to women continuing to cook with solid fuels for 18 months. Particulate matter ≤ 2.
J Appl Physiol (1985)
December 2024
Center for Hyperbaric Medicine and Environmental Physiology, Department of Anesthesiology, Duke University School of Medicine, Durham, NC, 27710, USA.
Breathing hyperoxic gas is common in diving and accelerates fatigue after prolonged and repeated exposure. The mechanism(s) remain unknown but may be related to increased oxidants that interfere with skeletal muscle calcium trafficking or impair aerobic ATP production. To determine these possibilities, C57BL/6J mice were exposed to hyperbaric oxygen (HBO) for 4-h on three consecutive days or remained in room air.
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