AI Article Synopsis
- Recent reports indicate that antiretroviral treatment failures are rising in sub-Saharan Africa, primarily due to poor adherence to treatment regimens.
- A study in Uganda involving 295 HIV-positive patients found that 11.2% missed at least one of their scheduled appointments over a 24-week period, with physical inactivity and depression being significant predictors of missed visits.
- The research suggests that future interventions aimed at improving treatment adherence should focus on addressing mental health issues and promoting physical activity among patients living with HIV.
Article Abstract
Alarming reports of antiretroviral treatment failure have recently emerged in sub-Saharan Africa. The onset of virologic failure has multiple causes but suboptimal treatment adherence is one of the leading causes. This study aimed to explore correlates of adherence to HIV appointments in community care patients living with HIV/AIDS in Uganda. Two hundred and ninety-five people living with HIV (median age 37.0 years; interquartile range 16.0; female 67.8% [ = 200]) reported whether they had missed any of their four-weekly appointments during the past 24 weeks. They also completed the Internalized AIDS-Related Stigma Scale, Generalized Anxiety Disorder-7, the Patient Health Questionnaire-9, the Alcohol-Use Disorders Identification Test, and the Physical Activity Vital Sign. Thirty-three (11.2%) patients missed at least one of their six scheduled appointments in the 24-week period. The adjusted odds ratio for missing at least one of six appointments was 3.03 (95% CI: 1.21-8.43, = 0.01) for those who were physically inactive, and 2.29 (95% CI: 0.93-5.63, = 0.046) for those with depression. Targeting future rehabilitation studies for PLHIV around feelings of depression and around physical inactivity could be important in achieving optimal HIV treatment adherence.
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| http://dx.doi.org/10.2989/16085906.2021.1895235 | DOI Listing |
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