Background: This article is the third in a commissioned series on paediatric orthopaedics. Developmental dysplasia of the hip (DDH) encompasses the pathological spectrum of hip instability that produces subluxation or dislocation and radiological features of abnormal acetabular development. It is important to approach DDH with sound prior knowledge to recognise, diagnose and manage its variety of presentations.
Objective: The aim of this article is to summarise contemporary practice in DDH with an emphasis on recent changes in diagnosis, surveillance and treatment recommendations for general practitioners (GPs), who see infants and toddlers in practice.
Discussion: The management of DDH requires accurate diagnosis of the pathoanatomy and depends on the age of the child. GPs are essential for the early detection of DDH, which then allows for harnessing of the remodelling potential of the hip cartilaginous anlage to achieve a stable and mature hip. GPs also play an important part in surveillance, and this article provides an update on the pivotal points.
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http://dx.doi.org/10.31128/AJGP-07-20-5543 | DOI Listing |
Radiol Case Rep
March 2025
Division of Neuroradiology, Joint Department of Medical Imaging, Toronto Western Hospital, Department of Medical Imaging, University of Toronto, Toronto, Ontario.
Pontine Tegmental Cap Dysplasia (PTCD) is a rare hindbrain malformation characterized by cranial nerve dysfunction, cerebellar abnormalities, and developmental delays of varying severity. This case report presents a 12-month-old female with significant developmental delays, hypotonia, and cranial nerve abnormalities. The findings underscore the critical role of radiology and neuroimaging in diagnosing and managing PTCD.
View Article and Find Full Text PDFPak J Med Sci
January 2025
Muhammad Ashfaq, MCPS, FCPS, CHPE (JSMU) Pediatric Medicine, National Institute of Child Health Karachi, Pakistan.
Objectives: To determine gender and ethnic distribution of developmental dysplasia of hip in newborns using Graf method for ultrasound. To determine the significance of association between developmental dysplasia of hip with ethnicity in newborns using Graf's method ultrasound.
Method: This analytical cross-sectional observational study was conducted in Karachi from January through June 2022 .
Bone Res
January 2025
Institute of Life Course and Medical Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor whose dysfunction is linked to developmental dysplasia of the hip, osteoporosis and osteoarthritis. Our work addresses the critical question of how these skeletal pathologies emerge. Here, we show the abundant expression of LRP1 in skeletal progenitor cells at mouse embryonic stage E10.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Orthopedics and Traumatology, Private Medicabil Hospital, 16140 Nilüfer/Bursa, Türkiye.
: Developmental dysplasia of the hip (DDH), defined by the malalignment of the femoral head and acetabulum, is a major precursor to coxarthrosis, posing substantial challenges during total hip arthroplasty (THA). Patients with coxarthrosis secondary to DDH often exhibit acetabular bone insufficiency, which makes challenging surgical reconstruction difficult. This study aimed to compare the radiologic and functional outcomes of robotically assisted and conventional manual THA techniques in patients with coxarthrosis secondary to Crowe type III-IV DDH.
View Article and Find Full Text PDFAnimals (Basel)
January 2025
Guide Dogs for the Blind, San Rafael, CA 94903, USA.
Using genetic selection, Guide Dogs for the Blind (GDB) has reduced the incidence rate of canine hip dysplasia (CHD). However, given that CHD is polygenic and multifactorial, environmental factors may impact the expression of this developmental condition. The objective of this original, correlational research was to investigate the relationship between the substrate in the whelping pool used from birth to 3 weeks of age and CHD diagnosis.
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