AI Article Synopsis
- A 71-year-old male experienced anaphylactic shock and was found to be resistant to adrenaline due to his beta-blocker medication, requiring glucagon to stabilize him.
- The patient also developed acute coronary syndrome, leading to the identification of two contributing mechanisms of Kounis syndrome: adrenaline-induced coronary spasm and an imbalance between oxygen supply and demand triggered by the allergic reaction.
- The patient’s beta-blocker treatment was stopped as his heart function remained stable, highlighting the need for careful reconsideration of using beta-blockers after severe allergic events in myocardial infarction recovery.
Article Abstract
A 71-year-old male patient reported to our hospital with anaphylactic shock, and the following two issues were focused in this case. First, he was resistant to adrenaline because of taking beta-blocker, and shock was repeated until glucagon administration was initiated. Second, he developed acute coronary syndrome. Two mechanisms contributing to Kounis syndrome were differentiated: 1) adrenaline induced coronary spasm and platelet activation or 2) a mismatch between oxygen supply and demand due to an allergic reaction. Beta-blocker therapy was discontinued because his cardiac function was preserved. Secondary preventive beta-blockers in recovering myocardial infarction with severe anaphylaxis history should be carefully considered.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293598 | PMC |
| http://dx.doi.org/10.1111/anec.12837 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!