Purpose: To evaluate the technical efficacy, safety, and reproducibility of automated percutaneous lumbar discectomy (APLD) under CT and fluoroscopic guidance, for treating radiculopathy caused by lumbar disc herniation in patients impervious to conservative treatment.
Methods: A total of 77 patients with symptomatic lumbar disc herniation were treated with APLD in a prospective multicentric study performed in four centers across three countries. Magnetic resonance imaging and/or computed tomography was used to evaluate the disc herniation before and after the procedure. Only local anesthesia was used during these procedures. Clinical outcomes were measured with the visual analog scale (VAS) for pain at one and 6 months after the procedure.
Results: Technical success rate was 100% with a mean intervention duration of 30 min (15-45 min). No complications occurred during the procedure. Post-lumbar puncture syndrome occurred in three patients who were successfully treated with blood patches. VAS decreased from a mean of 8 before the intervention to 3 1 month after (p value = 0.001). The requirement for analgesia decreased from 100 to 27%. No statistically significant differences in outcomes were found between the centers.
Conclusion: APLD with dual imaging guidance under local anesthesia is a safe, feasible, and reproducible technique to treat symptomatic lumbar disc herniation.
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http://dx.doi.org/10.1007/s00234-021-02633-x | DOI Listing |
Introduction: Increased fatty infiltration of the paraspinal muscles (PM) has been recognized as a sign of decreased muscle quality in patients with degenerative disc disease. However, whether fatty infiltration is a consequence of a neurogenic process due to spinal nerve root compression has not yet been determined.
Objective: To investigate the correlation between fatty infiltration of the paraspinal muscles (PM) and neurogenic remodeling of motor unit action potentials (MUAPs) in patients with lumbar radiculopathy.
Cureus
November 2024
Anesthesiology, Showa University School of Medicine, Tokyo, JPN.
Usually, coccydynia cases are caused by herniated discs, with lower back pain and sciatica as initial symptoms. However, whether lumbar disc herniation causes coccydynia without back pain remains unclear. We report a case of lumbar disc herniation diagnosed as the underlying cause of coccydynia by discoblock.
View Article and Find Full Text PDFFront Neurol
December 2024
Department of Radiology, Qujing Second People's Hospital, Qujing, China.
Background: CT-routine MRI fusion imaging has recently become available to evaluate spinal anatomy before surgery. Due to the 3-5 mm slice thickness and non-isotropic of routine MRI sequence, the CT-routine MRI fusion imaging is not good. The MRI multiple recalled gradient echo (MERGE) sequence is potentially useful in diagnosis of lumbar degeneration disease due to the better nerve roots visualization, 1 mm slice thickness and its isotropy.
View Article and Find Full Text PDFJ Orthop Surg Res
December 2024
Department of Orthopaedic Surgery, Japan Red Cross Aichi Medical Center Nagoya Daini Hospital, Myokencho 2-9, Syowa-Ku, Nagoya, Aichi, 466-8650, Japan.
Background: Low back pain is often caused by lumbar disc herniation (LDH). Treatment of LDH is possible using chemonucleolysis of the nucleus pulposus with condoliase injection. However, onset of the therapeutic effect varies among patients, with improvement from an early stage to 3 months post-injection.
View Article and Find Full Text PDFNeurol Int
December 2024
Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 135-896, Republic of Korea.
Animal models are valuable tools for studying the underlying mechanisms of and potential treatments for intervertebral disc diseases. In this review, we discuss the advantages and limitations of animal models of disc diseases, focusing on lumbar spinal stenosis, disc herniation, and degeneration, as well as future research directions. The advantages of animal models are that they enable controlled experiments, long-term monitoring to study the natural history of the disease, and the testing of potential treatments.
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