Nanobiotechnology is known as the application of nanoscaled techniques in biology which bridges natural science to living organism for improving the quality of life of humans. Nanotechnology was first issued in 1959 and has been rapidly developed, supplying numerous benefits to basic scientific academy and to clinical application including human healthcare, specifically in cancer therapy. This chapter discusses recent advances and potentials of nanotechnology in pharmaceutics, therapeutics, biosensing, bioimaging, and gene delivery that demonstrate the multifunctionality of nanotechnology.
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Recent advances in nanoarchitectonics of two-dimensional nanomaterials for dental biosensing and drug delivery.
Adv Colloid Interface Sci
December 2024
Department of Periodontology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, Nanjing 210008, China. Electronic address:
Two-dimensional (2D) nanoarchitectonics involve the creation of functional material assemblies and structures at the nanoscopic level by combining and organizing nanoscale components through various strategies, such as chemical and physical reforming, atomic and molecular manipulation, and self-assembly. Significant advancements have been made in the field, with the goal of producing functional materials from these nanoscale components. 2D nanomaterials, in particular, have gained substantial attention due to their large surface areas which are ideal for numerous surface-active applications.
View Article and Find Full Text PDFMultifunctional DNA-Metal Nanohybrids Derived From DNA-MgPPi Microhybrids by Rolling Circle Amplification.
Small Methods
January 2025
Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Rolling circle amplification (RCA)-derived ultra-long DNA is highly attractive and versatile because of its diverse functionalities conferred by repeated DNA nanostructures. However, magnesium pyrophosphate (MgPPi) crystals, as byproducts of RCA, electrostatically interact with the DNA to form DNA microhybrids and hamper its broad bioapplications, as its large size is unfavorable for cellular uptake and decreases the density of functional DNA nanostructures. In this study, finely tuned synthesis strategies are developed to condense the microhybrids and replace non-functional MgPPi crystals with various functional metal nanostructures by reducing metal ions.
View Article and Find Full Text PDFAdvances in peptide/polymer antimicrobial assemblies.
J Mater Chem B
December 2024
State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Qianjin Avenue 2699, Changchun 130012, China.
Antimicrobial peptides (AMPs) have been extensively exploited as promising drugs to cope with antibiotic-resistant bacteria in clinical treatment. Peptide/polymer assembly provides a particularly important contribution to this topic and has emerged as a new paradigm for the development of nano-antimicrobial systems with previously unattainable outcomes. In this review article, we systematically summarize the recent advances in antimicrobial peptide/polymer assemblies.
View Article and Find Full Text PDFTwo-dimensional metal-organic frameworks (2D-MOFs) as a carrier for enzyme immobilization: A review on design and bio-applications.
Int J Biol Macromol
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Department of Chemical Engineering, Institute of Chemical Technology, Matunga (E), Mumbai 400019, India. Electronic address:
In the realm of carriers for enzyme immobilization, the use of MOFs has accelerated owing to their exceptional porosity and stability. Among these, 2D metal-organic frameworks (2D-MOFs) have emerged as promising supports for enzyme immobilization. This review highlights advancements in their synthesis, structural properties, and functional characteristics, focusing on enhancing catalytic performance and stability.
View Article and Find Full Text PDFSolid-state self carbo-passivation for refurbishing colloidal dispersity of catalytic silica nanoreactors.
Mater Horiz
December 2024
Creative Research Initiative Center for Nanospace-confined Chemical Reactions (NCCR), Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.
Silica-based nanostructures are among the most utilized materials. However, a persistent challenge is their irreversible agglomeration upon drying and heat treatments, restricting their homogeneous colloidal re-dispersion - a mandatory requirement for diverse bio-applications. We address this bottleneck by developing a self carbo-passivation (SCP) strategy: silica nanoparticles (NPs), pre-included with the catalytic metal precursors and organosilanes undergo thermochemical conversion with highly controlled interior-to-surface segregation of nanometer-scale "carbonaceous skin patches".
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