Experimental and numerical investigation of pulsed flows in asevere aortic stenosed model.

Steady and pulsatile aortic stenotic flows through stenosis tubes were experimentally and numerically investigated. The objective was the understanding of the fluid dynamics in arterial geometries most relevant in the context of atherosclerosis. Axisymmetric phantoms corresponding to significant artery stenosis of 50% in diameter and severe aortic stenosis of 75% were respectively machined from silicon. A water flow circuit was established, a steady flow was provided by gravity and a pulsed flow by a pulsatile pump. At inlet Reynolds numbers in the range of 85 to 1125, flows at the stenosis region were investigated using two-component Particle Image Velocimetry (PIV). For the unsteady flow, three different heartbeats (60, 69 and 90 beats per minute) were considered. The k-ω shear-stress-transport first-order turbulence model in Computational Fluid Dynamics (CFD) commercial software was adopted for simulations. Experimental measurements of the velocity fields show good agreements with CFD for both steady and pulsed flows. Recirculation regions were found near the stenosis in both cases. Reverse flow through the stenosis was also observed in pulsatile flow during the end diastolic phase of the cycle. CFD simulations allowed us to accurately assess wall shear stress in the stenotic region where the optical measurements are very noisy. High values of wall shear stress (with high variations both in space and time), are observed, which are indicators of possible future aortic wall damage.