AI Article Synopsis
- Binge drinking is common among young adults and poses a risk for developing alcohol use disorder; the relationship between body mass index (BMI) and leptin levels with binge drinking needs further exploration.
- In a study of 192 young adults, binge drinkers had significantly higher BMI than non-binge drinkers, with this higher BMI correlating to more severe binge drinking episodes, especially in men.
- The findings reveal that while higher BMI is linked to binge drinking in men, there is a notable association between the soluble leptin receptor/BMI ratio and binge drinking in women, highlighting the need for more research on metabolic factors in binge drinking behaviors.
Article Abstract
Objective: Binge drinking is a highly prevalent behavior in adolescents and young adults and a risk factor to develop alcohol use disorder. Body mass index (BMI) and blood levels of leptin peptide and its soluble receptor have been implicated in alcohol use disorder; however, their role in binge drinking remains to be investigated.
Method: We studied associations of BMI, serum levels of soluble leptin receptor (ObRe) and leptin as well as the free leptin index with binge drinking in 93 male and 99 female young adults.
Results: In men, binge drinkers showed significantly higher BMI (kg/m) than non-binge drinkers (23.67 vs. 22.08) and higher BMI correlated significantly with more severe binge drinking episodes (ρ = 0.251). In women, we found significantly higher ObRe (ng/ml) / BMI (kg/m) values in binge drinkers than in non-binge drinkers (0.52 vs. 0.44) and ObRe/BMI values correlated significantly with more severe binge drinking episodes (ρ = 0.210).
Conclusion: This study confirms that higher BMI associates with binge drinking in men and shows for the first time a role of ObRe/BMI in binge drinking in women. Our data emphasize the importance of further research in the field of metabolic markers and implications in neurobiological processes of binge drinking.
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| http://dx.doi.org/10.1016/j.psyneuen.2021.105179 | DOI Listing |
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