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| http://dx.doi.org/10.1148/ryct.2020200557 | DOI Listing |
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Ferumoxytol-enhanced MR venography for mapping lower-extremity venous networks and evaluating varicose veins in patients with diabetes.
Eur Radiol
November 2024
Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Objectives: Comprehensive evaluation of lower-extremity varicose veins (VVs) in patients with diabetes is crucial for treatment strategizing. The study aims to assess the feasibility of using ferumoxytol-enhanced MR venography (FE-MRV) for lower-extremity venous mapping and the detection of VVs in patients with diabetes.
Materials And Methods: As part of a phase II clinical trial of a generic brand of ferumoxytol, documented patients with diabetes were enrolled and underwent FE-MRV on a 3-Τ MRI system.
Ferumoxytol-enhanced MR venography for diagnosis of venous thoracic outlet syndrome.
Radiol Case Rep
July 2023
Department of Radiology, University of California, Davis, 4860 Y St, Suite 3100, Sacramento, CA 95817, USA.
Venous thoracic outlet syndrome commonly results in arm swelling and pain as the subclavian vein is obstructed within the thoracic inlet. We report the use of ferumoxytol-enhanced contrast MRI in the diagnosis of venous thoracic outlet syndrome in a male adolescent. In this patient who presented with right upper extremity thrombosis, ferumoxytol-enhanced MRI of the chest was able to show both chronic subclavian vein thromboses and dynamic occlusion of the subclavian veins with arm abduction consistent with Paget-Schroetter syndrome.
View Article and Find Full Text PDFFerumoxytol-Enhanced Cardiac Magnetic Resonance Angiography and 4D Flow: Safety and Utility in Pediatric and Adult Congenital Heart Disease.
Children (Basel)
November 2022
Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences, 300 Medical Plaza, B119, Los Angeles, CA 90095, USA.
Cardiac magnetic resonance imaging and angiography have a crucial role in the diagnostic evaluation and follow up of pediatric and adult patients with congenital heart disease. Although much of the information required of advanced imaging studies can be provided by standard gadolinium-enhanced magnetic resonance imaging, the limitations of precise bolus timing, long scan duration, complex imaging protocols, and the need to image small structures limit more widespread use of this modality. Recent experience with off-label diagnostic use of ferumoxytol has helped to mitigate some of these barriers.
View Article and Find Full Text PDFHigh-resolution three‑dimensional contrast‑enhanced magnetic resonance venography in children: comparison of gadofosveset trisodium with ferumoxytol.
Pediatr Radiol
March 2022
Diagnostic Cardiovascular Imaging Research Laboratory, Department of Radiological Sciences, University of California at Los Angeles, Peter V. Ueberroth Building, Suite 3371, 10945 Le Conte Ave, Los Angeles, CA, 90095-7206, USA.
Background: Gadofosveset is a gadolinium-based blood pool contrast agent that was approved by the United States Food and Drug Administration in 2008. Its unanticipated withdrawal from production in 2016 created a void in the blood pool agent inventory and highlighted the need for an alternative agent with comparable imaging properties.
Objective: The purpose of our study is to compare the diagnostic image quality, vascular contrast-to-noise ratio (CNR) and temporal signal characteristics of gadofosveset trisodium and ferumoxytol at similar molar doses for high-resolution, three-dimensional (3-D) magnetic resonance (MR) venography in children.
Ferumoxytol-enhanced MR Venography of Central Veins: Commentary.
Radiol Cardiothorac Imaging
December 2020
Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Peter V. Ueberroth Bldg, Suite 3371, 10945 LeConte Ave, Los Angeles, CA 90095-7206.
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