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| http://dx.doi.org/10.1177/10781552211004680 | DOI Listing |
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Genetic and Structural Factors Contributing to the Dominance and Persistence of Goose Astrovirus Type 2.
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College of Animal Science and Technology/Veterinary Medicine, Anhui Agricultural University, Hefei, PR China.
Goose astrovirus (GoAstV) has emerged as a significant pathogen affecting the goose industry in China, with GoAstV-2 becoming the dominant genotype since 2017. This study explores the genetic and structural factors underlying the prevalence of GoAstV-2, focusing on codon usage bias, spike protein variability, and structural stability. Phylogenetic and effective population size analyses revealed that GoAstV-2 experienced rapid expansion between 2017 and 2018, followed by population stabilization.
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Department of Cardiovascular Surgery, Mayo Clinic Rochester, Rochester, Minnesota, USA.
Background: Population-based analyses may reduce uncertainty related to referral bias and/or incomplete follow-up.
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Department of Civil Engineering, The University of British Columbia, 6250 Applied Sciences Lane, Vancouver, British Columbia V6T 1Z4, Canada.
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Research Department of Behavioural Science and Health, University College London, London, United Kingdom.
The term Regulatory Disorders (RDs) refers to infants and young children who cry a lot, have poorly organised sleep-waking, or whose feeding is impaired. The characteristic they share is a failure to acquire autonomous self-control of these key behaviours, which most children develop in the first postnatal year. The concept of RDs is helpful in highlighting this question of how infant self-regulation is, or isn't, accomplished, in drawing these characteristics together and distinguishing them from others, and in focusing research and clinical attention on a common, but relatively neglected, set of concerns for families.
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