Genetic characterization of H9N2 avian influenza virus previously unrecognized in Korea.

J Vet Sci

Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea.

Published: March 2021

AI Article Synopsis

  • The study reports the isolation and characterization of new Y280-lineage H9N2 viruses from live bird markets in Korea as of June 2020.
  • Genetic analysis shows these viruses are distinct from previous H9N2 strains in Korea and closely related to a specific strain found in Shandong, China.
  • The viruses belong to genotype S, which has been associated with human infections and has contributed to the evolution of more dangerous H5 and H7 influenza viruses, highlighting the need for better surveillance and control measures.

Article Abstract

In this study, we describe the isolation and characterization of previously unreported Y280-lineage H9N2 viruses from two live bird markets in Korea in June 2020. Genetic analysis revealed that they were distinct from previous H9N2 viruses circulating in Korea and had highest homology to A/chicken/Shandong/1844/2019(H9N2) viruses. Their genetic constellation showed they belonged to genotype S, which is the predominant genotype in China since 2010, where genotype S viruses have infected humans and acted as internal gene donors to H5 and H7 zoonotic influenza viruses. Active surveillance and control measures need to be enhanced to protect the poultry industry and public health.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007441PMC
http://dx.doi.org/10.4142/jvs.2021.22.e21DOI Listing

Publication Analysis

Top Keywords

h9n2 viruses
8
viruses
5
genetic characterization
4
characterization h9n2
4
h9n2 avian
4
avian influenza
4
influenza virus
4
virus unrecognized
4
unrecognized korea
4
korea study
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!