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http://dx.doi.org/10.1016/S1473-3099(21)00149-3 | DOI Listing |
Nutrients
October 2024
School of Life Sciences, Jilin University, Changchun 130012, China.
Signal Transduct Target Ther
March 2024
Department of Oncology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Patients with advanced gastric cancer typically face a grim prognosis. This phase 1a (dose escalation) and phase 1b (dose expansion) study investigated safety and efficacy of first-line camrelizumab plus apatinib and chemotherapy for advanced gastric or gastroesophageal junction adenocarcinoma. The primary endpoints included maximum tolerated dose (MTD) in phase 1a and objective response rate (ORR) across phase 1a and 1b.
View Article and Find Full Text PDFJ Thorac Dis
February 2023
Radiation Oncology, Juravinski Cancer Center, McMaster University, Hamilton, Ontario, Canada.
Background: Radiotherapy (RT) is used as monotherapy in poor performance patients with unresected locally advanced non-small cell lung cancer (LA-NSCLC), but their outcomes are not well-described. As novel therapies are increasingly considered in this space, it is important to understand contemporary outcomes of RT alone. Here, in this retrospective cohort study we analyzed LA-NSCLC outcomes of RT alone in Ontario, Canada, and contrasted them against those of standard of care (SoC) treatment of concurrent chemo-radiotherapy (cCRT).
View Article and Find Full Text PDFLancet Infect Dis
August 2021
Edge BioInnovation and Healion Bio, Frederick, MD, USA. Electronic address:
ANZ J Surg
September 2013
Department of Surgery, Hanyang University Hospital, Seoul, Korea.
Background: The aim of this study was to investigate the hypothesis that prevention of surgical site infection (SSI) is equally effective when patients receive single-dose (SD) or three-dose antibiotic prophylaxis with second-generation cephalosporin and metronidazole in elective colorectal surgery.
Methods: Ninety-three patients were enrolled from May 2009 to November 2010. The SD group received only one preoperative prophylactic intravenous dose and the three-dose or multiple-dose (MD) group received one preoperative prophylactic and two additional post-operative doses of second-generation cephalosporin and metronidazole.
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