The purpose of this review is to describe the functional anatomy of the precuneal cortex and outline some semiological features of precuneal seizures. The precuneal cortex is a structure that occupies the posterior medial portion of the parietal lobe, and it has broad cortical and subcortical connections. Neuroanatomical tracing, functional imaging, as well as electrical stimulation studies of humans and other primates have elucidated many complex integrative functions of the precuneus including visuo-spatial imagery, sensorimotor functions, and consciousness. Based on the understanding of its functions and connectivity, descriptions of potential seizure semiologies are hypothesized and compared to what is available in the literature. The latter is mostly in the form of case reports or case series. Seizures may involve simple or complex motor or sensory manifestations including abnormal eye movements, visual hallucinations, sensation of motion, or medial temporal-like seizures.
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http://dx.doi.org/10.1684/epd.2021.1257 | DOI Listing |
Cereb Cortex
August 2024
Cognitive Neuroscience Unit, Montreal Neurological Institute, McGill University, 3801 University St, Montreal, Quebec H3A 2B4, Canada.
The executive control process of monitoring information in working memory depends on the mid-dorsolateral prefrontal cortical region (cytoarchitectonic areas 46 and 9/46) in interaction with the hippocampal memory system. Anatomical studies demonstrated strong connectivity between the mid-dorsolateral prefrontal cortex and the medial parietal area PGm that lies on the precuneus. Area PGm is also strongly connected with the attentional system on the lateral inferior parietal lobule (area PG) and the limbic retrosplenial/posterior cingulate region that interacts with the hippocampal memory system.
View Article and Find Full Text PDFSchizophr Res
May 2024
Department of Psychiatry, University of Colorado School of Medicine, Anschutz Medical Campus, Anschutz Health Sciences Building, 1890 N Revere Ct, Aurora, CO 80045, USA; Research Service, Rocky Mountain Regional VA Medical Center, 1700 N Wheeling St, Aurora, CO 80045, USA. Electronic address:
Epileptic Disord
April 2023
Departamento de Biomorfologia - Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Brazil.
Behav Neurosci
April 2023
Department of Education Nursing.
Previous studies have reported the importance of the precuneus in mediating metacognition and the prefrontal cortex in decision-making tasks. However, the mechanisms underlying metacognition remain to be fully elucidated. N-acetyl aspartate/creatine + phosphocreatine (NAA/Cr + PCr) is a putative neuronal marker level, which has been used in cognitive disorders.
View Article and Find Full Text PDFJ Neurosurg
June 2023
Departments of1Neurosurgery and.
Objective: The precuneus hosts one of the most complex patterns of functional connectivity in the human brain. However, due to the extreme rarity of neurological lesions specifically targeting this structure, it remains unknown how focal damage to the precuneus may impact resting-state functional connectivity (rsFC) at the brainwide level. The aim of this study was to investigate glioma-induced rsFC modulations and to identify patterns of rsFC remodeling that accounted for the maintenance of cognitive performance after awake-guided surgical excision.
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