Back from the Brink: EGFR Inhibition in Gastroesophageal Cancer.

Clin Cancer Res

Department of Surgery and Cancer, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, United Kingdom.

Published: June 2021

Gastroesophageal adenocarcinomas (GEA) remain difficult to treat with limited targeted therapeutics. Negative results from randomized trials of EGFR inhibitors (EGFRi) in patients with molecularly unselected GEA have hampered the development of EGFRi in the gastroesophageal cancer space. A recent study reopens the game..

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7617050PMC
http://dx.doi.org/10.1158/1078-0432.CCR-21-0533DOI Listing

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