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Fatal outcome related to drug reaction with eosinophilia and systemic symptoms: a disproportionality analysis of FAERS database and a systematic review of cases.
Front Immunol
December 2024
Department of Pharmacy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Drug rash with eosinophilia and systemic symptoms (DRESS) is a life-threatening severe cutaneous adverse reaction.
Objective: This study aims to study fatal DRESS cases using FAERS database and systematic review.
Methods: Data of the FDA Adverse Event Reporting System (FAERS) database were extracted and manipulated.
A Long Way From Home: A Rare Case of Cutaneous Metastasis to the Scalp of Hepatocellular Carcinoma.
Case Rep Dermatol Med
December 2024
Department of Dermatology, Dermatology Group of the Carolinas, Concord, North Carolina, USA.
Cutaneous metastases of hepatocellular carcinoma (HCC) are uncommon but important to recognize for timely diagnosis and management. We present a case of a 70-year-old man with a history of HCC who developed a painless nodule on the scalp. Histopathological examination and immunohistochemistry confirmed the nodule as cutaneous metastasis of HCC.
View Article and Find Full Text PDFAdvanced Neuroimaging and Clinical Findings in a Case of Linear Scleroderma En Coup De Sabre Presenting With Seizures.
Cureus
November 2024
Radiology, Grupo CT Scanner, Mexico City, MEX.
Scleroderma is a rare connective tissue disease categorized as systemic or localized. Linear subtype of localized scleroderma usually manifests as a cutaneous linear scar-like lesion most commonly on the scalp. It may present with neurologic, ophthalmologic, and rheumatologic symptoms.
View Article and Find Full Text PDFCutaneous ultrasound in the diagnosis and assessment of inflammatory activity in tinea capitis.
Australas J Ultrasound Med
November 2024
Department of Dermatology Hospital Universitario Puerta de Hierro Majadahonda Calle Joaquín Rodrigo, 1, Majadahonda 28222 Madrid Spain.
Introduction: Although the diagnosis of tinea capitis is mainly microbiological, the risk of evolution towards cicatricial alopecia in the most severe cases requires empirical treatment based on physical examination and complementary examinations.
Methods: Two patients were evaluated by physical examination, cutaneous ultrasound and microbiological examination.
Results: Ultrasound showed follicular widening and increased vascularization in Doppler mode.
Infantile Hemangioma With Aggressive, Early-Onset Ulceration, and Kasabach-Merritt-Like Phenomenon in a Newborn.
Pediatr Dermatol
December 2024
Section of Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Infantile hemangiomas (IH) are the most common benign tumors of infancy and progress through recognized stages of evolution including early proliferation, plateau, and involution. Ulceration is a common complication of IHs typically observed during the early proliferative stage characterized by rapid growth. In rare cases, ulceration is the primary clinical manifestation of IHs.
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