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http://dx.doi.org/10.1007/s00467-021-04958-4 | DOI Listing |
Membranoproliferative glomerulonephritis (MPGN) has previously been used as an umbrella term to describe a spectrum of hypocomplementemic glomerular diseases, which are rare causes of end stage kidney disease (ESKD). We present a 22-year-old man with a well-established medical history who had been complaining of 4 days of frothy dark urine, bilateral lower limb swelling, and puffiness on his face. For a month before his presentation, he had many bilateral skin lesions on his lower limbs that were leaking pus.
View Article and Find Full Text PDFIntroduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease predominantly affecting women, particularly in African American populations. While its physical health impacts are well-documented, patients also face significant psychosocial burdens, including barriers to healthcare access, financial constraints, mental health challenges, and inadequate social support.
Study Goal: This cross-sectional study surveyed 294 SLE patients recruited from Facebook and Reddit social media forums to examine how demographic factors such as age, race/ethnicity, and geographic location influence these burdens.
Arthritis Care Res (Hoboken)
January 2025
University of Manitoba, Winnipeg, Manitoba, Canada.
Objective: This study examined the lived employment experiences of young adults with childhood and adult-onset systemic lupus erythematosus (SLE).
Methods: Participants were recruited from three Canadian lupus clinics and asked to complete, semi-structured, qualitative video/phone interviews. Interviews were transcribed verbatim and analyzed using thematic analysis.
Front Pharmacol
December 2024
Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, China.
CAR-T cell therapy, a cutting-edge cellular immunotherapy with demonstrated efficacy in treating hematologic malignancies, also exhibits significant promise for addressing autoimmune diseases. This innovative therapeutic approach holds promise for achieving long-term remission in autoimmune diseases, potentially offering significant benefits to affected patients. Current targets under investigation for the treatment of these conditions include CD19, CD20, and BCMA, among others.
View Article and Find Full Text PDFTurk J Med Sci
December 2024
Division of Rheumatology, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkiye.
Background/aim: The transition from pediatric to adult-oriented care for individuals with juvenile-onset systemic lupus erythematosus (SLE) poses significant challenges. This study aimed to assess the outcomes of transitioning patients with juvenile-onset SLE from pediatric to adult-oriented care.
Materials And Methods: Patients with juvenile-onset SLE were included in the study.
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