A comprehensive work-up, clinical correlation, and differential diagnosis are needed to determine if abnormal findings such us hydromyelia in ALS patients are causative or incidental in order to rule out other, more curable conditions that resemble ALS.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981723PMC
http://dx.doi.org/10.1002/ccr3.3832DOI Listing

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