This case report aims to increase awareness that lichen nitidus may affect the mouth and therefore supports multidisciplinary management, particularly between dermatologists and dental professionals.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7981618 | PMC |
| http://dx.doi.org/10.1002/ccr3.3660 | DOI Listing |
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Postautologous Hematopoietic Stem Cell Transplantation Disseminated Hypopigmented Keratosis.
Am J Dermatopathol
December 2024
Department of Medicine, MacKay Medical College, New Taipei City, Taiwan; and.
Disseminated hypopigmented keratosis is a rare distinct clinical entity. This report describes the case of a 19-year-old male patient who developed disseminated hypopigmented keratosis 2 months after autologous hematopoietic stem cell transplantation for pineal choriocarcinoma. The patient displayed numerous tiny whitish or depigmented macules and papules on the chest, back, posterior neck, shoulders, arms, and thighs, closely resembling lichen nitidus.
View Article and Find Full Text PDFDermoscopic features of lichen nitidus.
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Article Synopsis
- Perforating lichen nitidus is a rare skin condition, with only about 11 cases documented globally, usually affecting young males in areas that experience frequent mechanical irritation like hands and elbows.
- The condition features distinct histopathological characteristics, including a specific lymphohistiocytic inflammation within the skin layers, leading to the elimination of dermal materials through the skin surface.
- This case study is notable as it describes the first instance of perforating lichen nitidus in a patient with atopic dermatitis undergoing dupilumab treatment, indicating that while atopic dermatitis improved, the lichen nitidus worsened, hinting at a unique underlying mechanism for the condition.
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